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Table 4 Effect of factors at ART initiation on mortality of patients

From: Determinants of time to antiretroviral treatment initiation and subsequent mortality on treatment in a cohort in rural northern Malawi

Factor

Unadjusted analysis

Adjusted analysis

Hazard ratio

95 % CI

p-value

Hazard ratio

95 % CI

p-value

Sex

  

0.016

  

0.040

Male

1 (ref)

  

1 (ref)

  

Female

0.57

0.36–0.90

 

0.61

0.38–0.98

 

Age

  

0.051

  

0.039

15–34

1 (ref)

  

1 (ref)

  

≥35

1.64

0.98–2.74

 

1.72

1.01–2.92

 

BMI

  

0.019

  

0.023

≥18.5

1 (ref)

  

1 (ref)

  

<18.5

1.82

1.12–2.95

 

1.65

1.00–2.72

 

Missing

3.02

1.08–8.41

 

3.97

1.33–11.91

 

CD4 count (cells/μL)

  

0.021

  

0.010

≤250

1 (ref)

  

1 (ref)

  

>250

0.66

0.28–1.54

 

0.60

0.25–1.47

 

Missing

1.87

1.13–3.10

 

2.09

1.19–3.69

 

WHO stage

  

<0.001

   

I & II

1 (ref)

     

III & IV

3.68

2.02–6.71

    

Year of ART initiation

  

0.535

  

0.859

2008

1 (ref)

  

1 (ref)

  

2009

1.07

0.57–2.01

 

0.95

0.49–1.84

 

2010

1.48

0.81–2.68

 

1.25

0.67–2.31

 

2011

1.46

0.68–3.12

 

1.07

0.47–2.45

 

Route of HIV testing

  

0.010

  

0.004

CRH

1 (ref)

  

1 (ref)

  

HIV serosurvey

0.47

0.28–0.81

 

0.43

0.25–0.74

 

Missing

1.07

0.55–2.07

 

1.07

0.54–2.10

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