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Table 2 Changes in Z-score neurocognitive testing parameters at weeks 24 and 48 from baseline

From: Evolution of changes in cognitive function after the initiation of antiretroviral therapy

Cognitive domain

Overall

n

Z-score change

SD of change

p value

Detectiona

 W24

14

0.10

0.68

0.59

 W48

12

−0.12

0.79

0.61

Identificationa

 W24

14

0.04

0.75

0.84

 W48

11

−0.08

0.99

0.78

Matched learninga

 W24

14

0.06

0.71

0.76

 W48

11

0.08

0.99

0.78

Monitoring timea

 W24

14

0.10

0.64

0.55

 W48

11

0.19

0.78

0.43

Associate learningb

 W24

13

0.01

0.08

0.65

 W48

10

0.19

0.64

0.36

One card learningb

 W24

14

0.17

1.27

0.62

 W48

12

0.11

1.46

0.78

Working memoryb

 W24

14

0.41

1.00

0.14

 W48

11

0.34

1.30

0.41

Composite speeda

 W24

14

0.07

0.37

0.45

 W48

11

0.05

0.67

0.82

Composite accuracyb

 W24

13

0.13

0.63

0.47

 W48

10

0.23

0.93

0.45

Global compositec

 W24

13

0.08

0.54

0.59

 W48

10

0.15

0.60

0.43

  1. All change estimates are based on pooled-standard-deviation standardized z-score changes
  2. N number of subjects, SD standard deviation of the change, CI confidence interval. Shaded areas, z-score changes
  3. aUsed to determine speed (sp); a positive change in z-score represents an improved response
  4. bUsed to determine accuracy (acc) of response; a positive change in z-score represents an improved response
  5. cA positive change in z-score represents an improved response. Global composite = composite accuracy + speed
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AIDS Research and Therapy

ISSN: 1742-6405

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