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Table 2 Comparison of reasons for treatment modification between older and younger patients

From: Factors associated with the first antiretroviral therapy modification in older HIV-1 positive patients

Reason for treatment modification

Patients less than 30

Patients from 30 to 50 y.o.

Patients over 50

P value*

Total

441 (100)

771 (100)

83 (100)

cART toxicity

136 (32.8)

232 (30.2)

30 (36.1)

0.41

cART failure

20 (4.8)

50 (6.5)

9 (10.8)

0.09

Non-HIV related disease

8 (1.9)

17 (2.2)

2 (2.4)

0.89

Non-adherence

116 (28.0)

262 (34.0)

13 (15.7)

<0.001

Pregnancy

12 (2.9)

1 (0.1)

0 (0.0)

<0.0001

Migration

21 (5.1)

55 (7.1)

3 (3.6)

0.15

Death

10 (2.4)

28 (3.6)

8 (9.6)

0.006

Other

65 (15.7)

80 (10.4)

13 (15.7)

0.07

Unknown

26 (6.3)

46 (6.0)

5 (6.0)

1.00

  1. * p value < 0.001