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Table 2 Predictors of Metabolic CVD risk factors among ARV treated HIV infected people

From: Assessment of cardiovascular risk factors in people with HIV infection treated with ART in rural South Africa: a cross sectional study

Predictor variable Metabolic CVD risk factors
HTN Diabetes Low HDL-C High TC High TG High TC/ HDL-C High Apo B/Apo A High TG/HDL-C Met S
Age (years)
 ≤50 1 [reference] 1 [reference] 1 [reference] 1 [reference] 1 [reference] 1 [reference] 1[reference] 1 [reference]
 >50 4.67 1 (1.94–11.2) 5.66 1 (1.36–23.5) 2.27 1(1.04–4.95)   2.91 1(1.12–7.55) 3.29 1 (1.35–8.01) 1.70 (0.90–3.21) 2.8 (0.84–5.68) 1.10 1 (1.02–1.18)
Gender
 Females 1 [reference] 1 [reference] 1 [reference]
 Males   1.83 (0.46–7.20)     2.94 1 (1.13–7.65)   1.90 (0.21–17.6)  
Alcohol use
 No 1 [reference] 1 [reference]
 Yes 0.57 (0.18–1.77)    1.69 (0.85–3.36)      
Tobacco use
 No 1 [reference] 1 [reference]
 Yes    0.49 (0.19–1.23)       1.61 (0.30–8.70)
Log VL  
 <1.71 1 [reference] 1 [reference] 1 [reference] 1 [reference]
 >1.71 0.08 1 (0.01–0.63)   3.82 1 (1.51–9.63)     3.83 1 (1.73–8.46) 2.71 (0.84–8.75)  
ARV-duration  
 >60 months 1 [reference] 1 [reference] 1 [reference] 1 [reference] 1 [reference]
 30–60 2.32 (0.65–8.34)     0.48 (0.14–1.68) 0.29 1 (0.09–0.90)   0.49 (0.13–1.87) 0.48 (0.09–2.75)
 <30 months 0.32 (0.66-8.19)     0.45 (0.14–1.46) 0.31 1 (0.11–0.89)   0.29 (0.07–1.23) 0.34 (0.05–2.60)
Abdominal obesity
 No 1 [reference] 1 [reference] 1 [reference] 1 [reference] 1 [reference] 1 [reference] _
 Yes 2.48 (0.69–8.89)   1.10 (0.26–4.66) 2.10 1 (1.09–4.05) 2.08 (0.75–5.82)   1.71 (0.88–3.35) 2.981 (1.05–8.47)  
PA (MET-min/wk)
 >600 1 [reference] 1 [reference]
 <600 0.27 (0.07–1.09)   0.54 (0.11–2.71)       
CD 4 count
 >500 1 [reference]
 301–500          0.31 (0.05–1.96)
 ≤300          0.12 (0.01–1.29)
F/veg intake 0.92 (0.18–4.79) 0.56* (0.31–1.01) 0.67 (0.41–1.10)
Abd. obesity by PA 7.18 (0.74–69.7)
Gender by ARV months
 >60         1 [reference]  
 30–60 0.46 (0.02–10.9)
 <30         6.07 (0.45–28.8)  
Classification accuracy 81.7 % 95.3 % 67.8 % 69.6 % 84.1 % 87.4 % 61.8 % 82.6 % 91.0 %
  1. Values are reported as adjusted odds ratio (confidence interval)
  2. PA physical activity, VL viral load, F/V fruit and vegetable intake, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, Apo B apolipoprotein B, Apo A apolipoprotein A, Met S metabolic syndrome, HTN hypertension, ARV antiretroviral, MET-min/wk metabolic equivalent of task-minute/week, Abd abdominal
  3. 1 p-value < 0.05 is significant
  4. * p = 0.05, marginally significant