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Table 2 Multivariate logistic regression analysis of factors associated with HIV viral load suppression ≤50 copies/ml on salvage ARTa

From: Third-line antiretroviral therapy in Africa: effectiveness in a Southern African retrospective cohort study

Variable

Unadjusted odds ratio (95 % CI)

p value

Adjusted odds ratio (95 % CI)

p value

Age (per year increase)

1.00 (0.95–1.05)

0.96

1.00 (0.94–1.06)

0.98

Female gender

2.42 (1.16–5.01)

0.02

2.45 (1.07–5.63)

0.04

HIV viral load at start of salvage ART (per log10 unit increase)

0.30 (0.17–0.53)

<0.001

0.38 (0.21–0.70)

0.002

Darunavir resistance score (per 10 point increase on Stanford database)

0.54 (0.38–0.76)

<0.001

0.59 (0.39–0.90)

0.01

Raltegravir in salvage regimen

1.11 (0.54–2.30)

0.77

2.38 (0.95–5.95)

0.06

  1. aAll 152 patients are included in this analysis. Those who did not have a viral load performed or who died before having a suppressed viral load recorded were regarded as having failed to suppress