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Table 1 Cox proportional hazards analysis of factors associated with time to mortality or loss to follow up

From: Community-based ART distribution system can effectively facilitate long-term program retention and low-rates of death and virologic failure in rural Uganda

List of clinical factors

Univariate

Multivariate

HR (95 % CI)

p value

HR (95 % CI)

p value

Age at ART initiation

0.99 (0.98, 1.00)

0.065

1.00 (0.99, 1.01)

0.720

First ARV regimen

 Nevirapine/zidovudine/lamivudine

1.00 (–)

0.018

1.00 (–)

0.003

 Efavirenz/stavudine/lamivudine

0.64 (0.39, 1.03)

 

0.87 (0.53, 1.44)

 

 Efavirenz/zidovudine/lamivudine

0.61 (0.42, 0.89)

 

0.74 (0.51, 1.09)

 

 Nevirapine/stavudine/lamivudine

0.91 (0.74, 1.14)

 

1.38 (1.08, 1.76)

 

 Other ARV regimen

1.21 (0.86, 1.71)

 

1.41 (1.00, 1.99)

 

WHO stage

 Stages 1 and 2

1.00 (–)

<0.001

1.00 (–)

0.002

 Stage 3

1.52 (1.24, 1.85)

 

1.36 (1.1, 1.67)

 

 Stage 4

1.82 (1.3, 2.56)

 

1.72 (1.21, 2.43)

 

CD4 at ART initiation

 ≥200

1.00 (–)

<0.001

1.00 (–)

<0.001

 50–199

2.21 (1.75, 2.8)

 

1.86 (1.46, 2.37)

 

 <50

5.25 (4.07, 6.78)

 

4.11 (3.13, 5.4)

 

District of residence at ART initiation

 Jinja

1.00 (−)

0.879

1.00 (–)

0.562

 Buikwe

0.87 (0.65, 1.15)

 

0.92 (0.69, 1.22)

 

 Iganga

0.87 (0.65, 1.15)

 

0.77 (0.58, 1.03)

 

 Kamuli

0.92 (0.66, 1.28)

 

0.92 (0.66, 1.28)

 

 Mayuge

0.95 (0.7, 1.27)

 

0.95 (0.7, 1.28)

 

 Other

0.85 (0.55, 1.31)

 

0.77 (0.5, 1.19)

 

Education level

 None/preprimary/other

1.00 (–)

0.587

1.00 (–)

0.400

 Higher education

0.89 (0.5, 1.58)

 

0.73 (0.39, 1.38)

 

 Some secondary

0.91 (0.67, 1.25)

 

0.81 (0.58, 1.12)

 

 Some primary

1.07 (0.82, 1.39)

 

0.97 (0.74, 1.28)

 

Gender

 Female

1.00 (–)

<0.001

1.00 (–)

<0.001

 Male

1.62 (1.34, 1.96)

 

1.6 (1.3, 1.97)

 

Occupation

 Peasant

1.00 (–)

0.136

1.00 (–)

0.065

 Casual laborer

1.24 (0.9, 1.72)

 

1.13 (0.81, 1.58)

 

 None

1.32 (1.02, 1.71)

 

1.34 (1.02, 1.74)

 

 Other

1.15 (0.83, 1.6)

 

1.13 (0.8, 1.58)

 

 Paid employee

1.01 (0.7, 1.45)

 

0.92 (0.61, 1.39)

 

 Vendor/business person

0.86 (0.63, 1.17)

 

0.79 (0.57, 1.08)

 

Year of ART initiation

1.39 (1.29, 1.51)

<0.001

1.32 (1.2, 1.46)

<0.001