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Table 5 Adjusted hazard ratios with confidence intervals from a Cox model after multiple imputation for all deaths during TB treatment according to age group (<45 years vs. ≥45 years of age)

From: Independent predictors of tuberculosis mortality in a high HIV prevalence setting: a retrospective cohort study

 

<45 years of age

≥45 years of age

aHR (95 % CI)

p value

aHR (95 % CI)

p value

Sex female

0.98 (0.83–1.16)

0.802

1.11 (0.86–1.44)

0.423

Anatomic site of TB

 Pulmonary

Reference

 

Reference

 

 Extra-pulmonary

1.16 (0.92–1.47)

0.213

1.20 (0.84–1.69)

0.313

 Both

1.52 (1.14–2.01)

0.004

1.21 (0.72–2.05)

0.473

Prior TB

1.10 (0.92–1.33)

0.299

1.31 (1.01–1.70)

0.042

HIV infected

3.16 (2.34–4.27)

<0.001

1.18 (0.87–1.59)

0.282

TB smear result

 Smear negative

Reference

 

Reference

 

 Smear positive

0.99 (0.81–1.21)

0.904

0.76 (0.56–1.02)

0.068

 No smear performed

1.21 (0.94–1.56)

0.142

0.87 (0.57–1.31)

0.501

  1. TB tuberculosis, ART antiretroviral treatment, TMP-SMX trimethoprim sulfamethoxazole 160/80 mg chemoprophylaxis, aHR adjusted hazard ratio, 95 % CI 95 % confidence interval