Table 4 Cox proportional hazards model of risk factors for development of AIDS
Risk factor | Unadjusted relative hazard | P | Adjusted relative hazard | P |
|---|---|---|---|---|
HR (95Â % CI) | HR (95Â % CI) | |||
Sex | ||||
 Male | 1 (reference) |  | – | – |
 Female | 0.996 (0.827–1.200) | 0.966 | – | – |
Age (year) | ||||
 0~ | 1 (reference) |  | 1 (reference) |  |
 25~ | 1.176 (0.949–1.457) | 0.139 | 1.221 (0.982–1.518) | 0.072 |
 35~ | 1.310 (1.031–1.666) | 0.027 | 1.364 (1.065–1.746) | 0.014 |
 45~ | 1.556 (1.167–2.075) | 0.003 | 1.692 (1.247–2.297) | 0.001 |
 55~ | 1.950 (1.412–2.694) | 0.000 | 1.915 (1.357–2.703) | 0.000 |
Education | ||||
 Primary school and under | 1 (reference) |  | – | – |
 Junior high school | 0.981 (0.798–1.206) | 0.856 | – | – |
 Senior high school | 0.943 (0.739–1.205) | 0.641 | – | – |
 College and above | 0.874 (0.673–1.135) | 0.312 | – | – |
Marital status | ||||
 Single | 1 (reference) |  | – | – |
 Married | 1.198 (1.007–1.425) | 0.042 | – | – |
 Divorced or widowed | 1.094 (0.863–1.386) | 0.457 | – | – |
 Unknown | 1.313 (0.486–3.526) | 0.590 | – | – |
Mode of transmission | ||||
 Homosexual contact | 1 (reference) |  | 1 (reference) |  |
 Heterosexual contact | 1.019 (0.862–1.205) | 0.824 | 0.695 (0.571–0.844) | 0.000 |
 Blood | 0.789 (0.514–1.212) | 0.279 | 0.524 (0.336–0.816) | 0.004 |
 Other and unknown | 0.951 (0.470–1.927) | 0.890 | 0.689 (0.336–1.415) | 0.311 |
Testing mode | ||||
 VCT consultant | 1 (reference) |  |  | – |
 Health checkup | 1.027 (0.807–1.306) | 0.831 | – | – |
 Seeing doctor for other disease | 1.261 (1.006–1.579) | 0.044 | – | – |
 Spouse and children of patient, blood donors | 1.380 (1.007–1.891) | 0.045 | – | – |
 Others | 1.112 (0.720–1.718) | 0.633 | – | – |
Census register | ||||
 Zhejiang Province | 1 (reference) |  | 1 (reference) |  |
 Other Province | 0.765 (0.651–0.898) | 0.001 | 0.670 (0.562–0.799) | 0.000 |
Mobility | ||||
 Between Provinces | 1 (reference) |  | – | – |
 Between Cites | 0.905 (0.636–1.287) | 0.579 | – | – |
 Between County | 0.977 (0.777–1.228) | 0.840 | – | – |
 Immobility | 0.970 (0.795–1.182) | 0.761 | – | – |
Reported time (year) | ||||
 2008–2010 | 1 (reference) |  | 1 (reference) |  |
 2011–2012 | 0.346 (0.274–0.437) | 0.000 | 0.382 (0.302–0.483) | 0.000 |
Baseline CD4+ T-cell count | ||||
 200–350 | 1 (reference) | 0.000 | 1 (reference) |  |
 350–500 | 0.464 (0.388–0.556) | 0.000 | 0.380 (0.316–0.458) | 0.000 |
 >500 | 0.262 (0.206–0.332) | 0.000 | 0.187 (0.147–0.239) | 0.000 |
CD4+ T-cell count of initial HAART | ||||
 No HAART | 1 (reference) |  | 1 (reference) |  |
 ≤200 | 2.166 (1.273–3.685) | 0.004 | 1.165 (0.679–1.999) | 0.580 |
 200–350 | 0.402 (0.320–0.504) | 0.000 | 0.225 (0.178–0.285) | 0.000 |
 >350 | 0.295 (0.110–0.789) | 0.015 | 0.168 (0.063–0.451) | 0.000 |