Skip to main content

Table 3 HIV-1 viral load and CD4+ T cell counts of individuals with major protease inhibitor drug resistance mutations

From: HIV-1 protease inhibitor drug resistance in Kenyan antiretroviral treatment-naive and -experienced injection drug users and non-drug users

ID Mutation Age, years Gender ART duration, years HIV-1 RNA (log10 HIV-1 RNA), copies/ml CD4+ T cells/ml
#1 D30N + M46I + G48E 36.4 M <0.5 4624 (3.7) 473
#2 L90M + K20R 34.6 M 1–3 291,124 (5.5) 637
#3 D30N + M46I + K20I 30.1 F 1–3 141,341 (5.2) 39
#4 D30N + T74S + K20R 33.3 M Naive 209,871 (5.3) 162
  1. Mutations are denoted according to Stanford drug resistance database and International Antiviral Society-USA drug resistance mutations panel [12, 39, 40]
  2. Major mutations are shown in bold
  3. D aspartic acid, E glutamic acid, G glycine, I isoleucine, K lysine, L leucine, M methionine, N asparagine, S serine; T threonine, ART antiretroviral therapy, HIV-1 human immunodeficiency virus type-1