Characteristic | Symptomatic acute group | Symptomatic recent group | Asymptomatic recent group | p value |
---|---|---|---|---|
Number of participants | 91 | 72 | 47 | Â |
Age at first visit (y), median [IQR] | 33 [28–38] | 30 [25–35] | 31 [24–36] | 0.0841 |
Men, n (%) | 91 (100%) | 69 (97%) | 47 (100%) | 0.0387 |
Estimated route of transmission, n (%) | Â | Â | Â | Â |
 Homosexual | 79 (87%) | 66 (92%) | 43 (92%) | 0.3234 |
 Heterosexual | 9 (10%) | 6 (8%) | 2 (4%) |  |
 Unknown | 3 (3%) | 0 (0%) | 2 (4%) |  |
HIV-1 subtype | Â | Â | Â | Â |
 B | 41 (45%) | 40 (56%) | 27 (57%) | 0.0983 |
 CRF01_AE | 0 (0%) | 1 (1%) | 2 (4%) |  |
 Not determined | 50 (55%) | 31 (43%) | 18 (38%) |  |
Nationality, n (%) | Â | Â | Â | Â |
 Japanese | 89 (98%) | 70 (97%) | 47 (100%) | 0.3490 |
 Other | 2 (2%) | 2 (2%) | 0 (0%) |  |
Calendar year at diagnosis, (%) | Â | Â | Â | Â |
 2007–2010 | 65 (71%) | 45 (63%) | 20 (43%) | 0.0044 |
 2003–2006 | 26 (29%) | 27 (37%) | 27 (57%) |  |
Medical exam between last negative and first positive test, n (%) | Â | Â | Â | Â |
 No | 3 (3%) | 26 (36%) | 47 (100%) | <0.0001 |
 Outpatient | 28 (31%) | 36 (50%) | 0 (0%) |  |
 Hospitalization | 60 (66%) | 10 (14%) | 0 (0%) |  |
Interval between last negative and first positive test (mo), median [IQR] |  | 7.1 [4.1–10.2] | 10.1 [6.1–11.7] | 0.0472 |
Baseline CD4 cell count (cells/μL), median [IQR] | 359 [243–464] | 353 [257–481] | 445 [353–526] | 0.0323 |
Percentage of patients with CD4 cell count <400 cells/μL, n (%) | 54 (59%) | 43 (60%) | 15 (31%) | 0.0035 |
Baseline HIV-1 RNA level (copies/mL), median [IQR] | 470000 [52000–270000] | 32000 [6900–74800] | 21000 [12000–66000] | <0.0001 |
Percentage of patients with HIV-1 RNA level ≥50000 copies/mL, n (%) | 69 (76%) | 26 (36%) | 14 (30%) | <0.0001 |