Skip to main content

Table 1 Subject Demographic, Virologic and Immunologic Parameters

From: Determination of HIV-1 coreceptor tropism using proviral DNA in women before and after viral suppression

  

Coreceptor Tropism Status 2

 

Median (IQR) 1

All Subjects

Concordant R5

Concordant

non-R5

Discordant

p-value 3

N

49

28

10

11

 

Age (years)

38 (33, 43)

39 (32,33)

36 (32, 38)

40 (34, 44)

0.62

Nadir CD4+

(cell/uL)

191 (87, 269)

194 (106, 270)

138 (44, 249)

191 (83, 285)

0.58

T1 CD4+

(cells/uL)

323 (243, 417)

321 (235, 404)

276 (234, 375)

345 (276, 537)

0.70

T1 viral load

(log10 copies/mL)

4.8 (4.4, 5.3)

4.7 (4.2, 5.3)

5.1 (4.5, 5.4)

4.8 (4.4, 5.3)

0.41

Delta T1 and T2 (years)

4.1 (2.6, 5.1)

3.1 (2.3, 4.7)

4.2 (2.7, 5.4)

4.3 (3.3, 6.2)

0.28

T2 CD4+

(cells/uL)

558 (365, 717)

576 (258, 747)

478 (294, 772)

532 (371, 666)

0.81

  1. 1T1: Time point 1, viremic subjects pre-suppression; T2: Time point 2, after subjects had undetectable viral load (<80 copies/mL) for ≥1 year.
  2. 2Concordant R5: CCR5-tropic viral RNA at T1 and proviral DNA at T1 and T2; Concordant non-R5: CXCR4-tropic viral RNA at T1 and proviral DNA at T1 and T2; Discordant: at least 1 discordant tropism result at T1 or T2.
  3. 3Kruskall-Wallis test for difference in distributions among tropism status categories.
Back to article page

AIDS Research and Therapy

ISSN: 1742-6405

Contact us