From: Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents 2014, Thailand
Generic Name | Abbreviation | Dosage form | Adult dose |
---|---|---|---|
Nucleoside reverse transcriptase inhibitors (NRTIs) | Â | ||
Lamivudine | 3TC | 150, 300 mg, 10 mg/ml | 150 mg q 12 h or 300 mg OD |
Abacavir | ABV | 300 mg | 300 mg q 12 h or 600 mg OD |
Zidovudine | AZT | 100, 300 mg, 10 mg/ml | 200 - 300 mg q 12 h |
Stavudine | d4T | 15, 20, 30 mg | 30 mg q 12 h |
5 mg/ml | |||
Didanosine | DDI | 250, 400 mg (extended release capsule) | ≤60 kg 250 mg OD, > 60 kg 400 mg OD |
25, 125, 200 mg (Buffer tablet) | with TDF ≤60 kg 200 mg OD, > 60 kg 250 mg OD on empty stomach | ||
Tenofovir | TDF | 300 mg | 1 tab OD |
Combined NRTIs | Â | Â | Â |
Zidovudine + Lamivudine | AZT/3TC | 300/150 mg | 1 tab q 12 h |
Abacavir + Lamivudine | ABV/3TC | 600/300 mg | 1 tab OD |
Tenofovir + Emtricitabine | TDF/FTC | 300/200 mg | 1 tab OD |
Stavudine + Lamivudine | D4T/3TC | 30/150 mg | 1 tab q 12 h |
Non-Nucleoside reverse transcriptase inhibitors (NNRTIs) | Â | ||
Rilpivirine | RPV | 25 mg | 1 tab OD with meal |
Efavirenz | EFV | 50, 200, 600 mg | 600 mg OD hs, on empty stomach to reduce side effect |
Etravirine | ETR | 100 mg | 2 tab q 12 h with meal |
Nevirapine | NVP | 200 mg, 10 mg/ml | 200 mg q 12 h or 400 mg OD |
Combine NRTIs + NNRTIs |  |  |  |
Tenofovir + Emtricitabine + Efavirenz | TDF/FTC/EFV | 300/200/600 mg | 1 tab OD hs, on empty stomach to reduce side effect |
Stavudine + Lamivudine + Nevirapine | GPO vir S | 30/150/200 mg | 1 tab q 12 h |
Zidovudine + Lamivudine + Nevirapine | GPO vir Z 250 | 250/150/200 mg | 1 tab q 12 h |
Protease inhibitors (PIs) | Â | Â | Â |
Atazanavir | ATV | 200, 300 mg | 300 mg OD (boosted rtv), 400 mg OD, with TDF 300 mg OD (boosted rtv) with EFV |
400 mg (boosted rtv), with meal | |||
Darunavir | DRV | 300, 600 mg | 600 mg q 12 h, 800 mg OD with meal |
Indinavir | IDV | 200, 400 mg | 800 mg q 12 h |
Lopinavir/ritonavir | LPV/rtv | 100/25, 200/50 mg, 80/20 mg/ml | 400/100 mg q 12 h or 800/200 mg OD |
Ritonavir | RTV | 100 mg | boosted RTV 100 mg q12 h or OD |
Saquinavir | SQV | 500 mg | 2 tab q 12 h |
CCR5 Inhibitor (CCR5I) | Â | Â | Â |
Maraviroc | MRV | 150, 300 mg | 150 mg q 12 h with strong cyp 3A inh. (with or without 3A ind.) ex. PIs except TPV/r |
 |  |  | 300 mg q 12 h with NRTIs, T20, NVP, RAL,TPV/r and other drug that not strong 3A inh./ind. |
 |  |  | 600 mg q 12 h with cyp 3A ind ex. EFV, ETR (without 3A inh.) |
Integrase inhibitors | Â | Â | Â |
Raltegravir 400 mg | RAL | 400 mg | 1 tab q 12 h |