In vitro inhibition of HIV replication by different drug treatments: Quinacrine (A) and Chloroquine (B). HIV p24 antigen (ng/ml) was measured in supernatants of cultures of peripheral blood mononuclear cells, infected with the HIVSF33 strain. Cells were treated during 4 days with 3′-azido-3′-deoxythymidine (AZT) (control), Quinacrine (Qc), Chloroquine (Cq) or the mixtures Qc-AZT or Cq-AZT. Each bar represents the mean +/− standard error of three independent assays by triplicate (n = 9). One-way ANOVA, followed by Tukey’s post-hoc test, was used to compare: A, Control (AZT) and Qc or AZT- Qc; and B, Control (AZT) and Cq or AZT-Cq. Statistical significant p-values are shown in the figure.