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Table 1 Baseline characteristics of antiretroviral therapy naïve 147 HIV-infected children

From: Association of APOBEC3G genotypes and CD4 decline in Thai and Cambodian HIV-infected children with moderate immune deficiency

Characteristics1 Total (n=147) APOBEC3G subtype AA (n=127) APOBEC3G subtype AG (n=17) APOBEC3G subtype GG(n=3) P value
Age (years) 6.5 (4.3-8.8) 6.7 (4.3-8.8) 6.3 (4.2-7.9) 2.8 (1.2-10.1) 0.55
% male 35% 35% 35% 33% 0.99
% CDC clinical classification N:A:B 1:63:36% 1:67:32% 6:35:59% 0:33:67% 0.05
Weight (kg) 17 (13.5-21.5) 17 (14–21.5) 16 (13.5-21) 11.5 (8.6-21) 0.39
Height (cm) 108 (95–121) 110 (95–121) 103 (99–115) 86 (70–120) 0.39
Weight for age z-score −1.32 (−2.03 to −0.79) −1.27 (−2.02 to −0.77) −1.33 (−2.03 to −0.89) −1.66 (−2.11 to −1.32) 0.72
Height for age z-score −1.66 (−2.5 to −0.93) −1.66 (−2.48 to −0.97) −1.39 (−2.33 to −0.87) −2.72 (−3.01 to −1.83) 0.30
Weight for height z-score −0.43 (−1.22 to 0.09) −0.44 (−1.22 to 0.12) −0.54 (−1.11 to −0.27) 0.03 (−0.4 to 0.37) 0.32
Baseline CD4% 20 (17–23) 20 (17–23) 19 (17–26.5) 22 (17–23) 0.81
Baseline CD4 count (cells/mm3) 605 (460–846) 601 (449–846) 620 (551–836) 1333 (675–2195) 0.09
Baseline HIV-RNA (log10copies/mL) 4.7 (4.3-5.0) 4.6 (4.3-5) 4.9 (4.4-5) 5 (3.9-5.5) 0.43
  1. 1Data are presented as median (IQR).
  2. APOBEC3G genotypes AA (186H/H), AG (186H/R), GG (186R/R).