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Table 2 Association between lopinavir trough concentrations and lipid and glucose concentrations

From: Association of lopinavir concentrations with plasma lipid or glucose concentrations in HIV-infected South Africans: a cross sectional study

 

Univariate analyses

Multivariate analyses

Variable

Beta coefficient (95%CI)

P value

Beta coefficient (95% CI)

P value

Total cholesterol

−0.04 (−0.07 to 0.00)

0.07

−0.02 (−0.06 to 0.01)

0.21

Triglycerides

−0.01 (−0.04 to 0.02)

0.53

−0.00 (−0.03 to 0.02)

0.86

Fasting glucose

−0.01 (−0.04 to 0.02)

0.44

−0.00 (−0.03 to 0.02)

0.78

2 hour glucose

−0.02 (−0.09 to 0.06)

0.64

0.00 (−0.05 to 0.06)

0.85

  1. Adjusted for time after dose, age, sex and duration on lopinavir. In the multivariate model for 2 hour glucose, time after dose was an independent predictor [β-coefficient 0.56 (95% CI 0.23 to 0.88), p= 0.001].