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Table 6 Associations of variables with abnormal lipid profiles among first-line HAART treated patients in Hawassa, Southern Ethiopia

From: Prevalence of dyslipidemia among HIV-infected patients using first-line highly active antiretroviral therapy in Southern Ethiopia: a cross-sectional comparative group study

Explanatory variables

Outcome

variables

  

TC ≥ 200 mg/dl

HDL-c < 40 mg/dl

LDL-c ≥ 130mg/dl

TG ≥150 mg/dl

BMI > 25kg/m2

    

UOR (95% CI)

3.09 (1.18-8.05)*

0.50 (0.19-1.33)

2.68 (1.05-6.85)*

2.71 (0.98-7.50)

AOR (95% CI)

3.21 (1.16-8.91)*

0.49 (0.17-1.39)

2.44 (0.91-6.51)

2.92 (0.99-8.44)

Gender (male)

    

UOR (95% CI)

0.93 (0.42-2.04)

1.28 (0.58-2.80)

0.49 (0.20-1.19)

1.14 (0.52-2.51)

AOR (95% CI)

0.68 (0.23-2.04)

0.69 (0.24-1.96)

0.43 (0.13-1.46)

1.09 (0.40-2.99)

Age > 40 years

    

UOR (95% CI)

3.13 (1.28-7.63)*

3.14 (1.29-7.64)*

2.08 (0.86-5.00)

1.97 (0.80-4.84)

AOR (95% CI)

4.43 (1.54-12.72)**

4.22 (1.46-12.16)**

4.28 (1.41-12.97)*

2.12 (0.77-5.82)

HAART ≤ 2 years

    

UOR (95% CI)

0.95 (0.24-3.75)

0.35 (0.08-1.49)

1.85 (0.37-9.39)

1.00 (0.26-3.97)

AOR (95% CI)

0.76 (0.16-3.66)

0.30 (0.06-1.47)

1.35 (0.22-8.20)

0.92 (0.21-4.09)

Current smoking

    

UOR (95% CI)

0.64 (0.11-3.64)

1.33 (0.26-6.87)

0.38 (0.04-3.36)

0.78 (0.15-4.06)

AOR (95% CI)

0.77 (0.12-5.79)

0.70 (0.10-4.80)

0.51 (0.04-5.82)

0.78 (0.12-5.04)

Past smoking

    

UOR (95% CI)

1.17 (0.39-3.47)

1.17 (0.39-3.47)

0.45 (0.12-1.70)

1.22 (0.40-3.70)

AOR (95% CI)

0.82 (0.20-3.34)

0.62 (0.16-2.45)

0.39 (0.08-1.98)

0.88 (0.23-3.40)

d4T

    

UOR (95% CI)

1.02 (0.48-2.15)

1.18 (0.56-2.49)

0.92 (0.42-2.02

1.05 (0.50-2.21)

AOR (95% CI)

1.29 (0.57-2.93)

1.41 (0.63-3.16)

1.22 (0.52-2.85)

1.17 (0.53-2.58)

EFV

    

UOR(95% CI)

0.75 (0.35-1.60)

1.36 (0.64-2.89)

0.78 (0.35-1.75)

0.91 (0.43-1.93)

AOR (95% CI)

0.77 (0.33-1.79)

1.36 (0.60 3.12)

0.91 (0.37-2.22)

0.97 (0.43-2.18)

  1. HAART, highly active antiretroviral therapy therapy; UOR, un adjusted odds ratio; AOR, adjusted odds ratio; CI, confidence interval; TC, total cholesterol; HDL-c, high-density lipoprotein cholesterol; LDL-c, low- density lipoprotein cholesterol; TG, triglyceride; d4T Stavudine; BMI, body mass index; EFV, Efavirenz; * p-value < 0.05; ** p-value < 0.01. Reference category: BMI ≤ 25 Kg/m2, Females, Age ≤ 40 years, no smoking, Nevirapine group, Zidovudine group; HAART treatment >2years.