Table 2 Association of baseline characteristics with outcomes among ART-eligible HIV-infected children enrolled in the Paediatric HIV programme, MRC Unit, The Gambia, 2004–2010
Variable | Started ART | Died | LTFU | Transferred | p-value |
|---|---|---|---|---|---|
Total (n=223) | 73 (32.7%) | 30 (13.5%) | 105 (47.1%) | 15 (6.7%) | Â |
Sex: (n=223) | |||||
Female | 35 (34.7%) | 12 (11.8%) | 48 (47.5%) | 6 (5.9%) | 0.868‡ |
Male | 38 (31.2%) | 9 (7.4%) | 57 (46.7%) | 18 (14.7%) | Â |
Age at eligibility: (n=222) | |||||
Median in years (IQR) | 4.7 (1.9 – 8.4) | 5.1 (1.6 – 10.0) | 1.9 (1.2 – 4.7) | 7.4 (3.2 – 8.7) | 0.0001 ψ |
< 2 years | 19 (21.4%) | 10 (11.2%) | 57 (64.0%) | 3 (3.4%) |  |
2 – 4 years | 21 (42.9%) | 5 (10.2%) | 22 (44.9%) | 1 (2.0%) |  |
≥ 5 years | 33 (38.8%) | 15 (17.7%) | 26 (30.6%) | 11 (12.9%) | <0.001 Ω |
HIV type: (n=223) | |||||
HIV-1 | 68 (31.8%) | 30 (14%) | 103 (48.1%) | 13 (6.1%) | 0.065 Ω |
HIV-2 | 5 (55.6%) | 0 | 2 (22.2%) | 2 (22.2%) | Â |
WHO stage: (n=178) | |||||
1 or 2 | 34 (54%) | 8 (12.7%) | 16 (25.4%) | 5 (7.9%) | Â |
3 or 4 | 33 (28.7%) | 16 (13.9%) | 59 (51.3%) | 7 (6.1%) | 0.003 Ω |
CD4% at eligibility: (n=196) | |||||
Median (IQR) | 11% (8 – 14) | 8% (4 – 11) | 11% (8 – 15.0) | 13% (8 – 14) | 0.039 ψ |
<15% | 55 (36.4%) | 25 (16.6%) | 60 (39.7%) | 11 (7.3%) | 0.574 Ω |
≥15% | 18 (40.0%) | 4 (8.9%) | 21 (46.7%) | 2 (4.4%) |  |
Haemoglobin: (n=192) | |||||
Median (IQR) | 9.6 (7.9 – 10.6) | 9.5 (7 – 11.4) | 9.1 (8.1 – 9.9) | 10 (8.6 – 10.5) | 0.262ψ |
< 8 g/dl | 20 (40%) | 9 (18%) | 20 (40%) | 1 (2%) | 0.245 Ω |
Vital status of parent: (n=173) | |||||
Single orphan | 25 (35.7%) | 6 (8.6%) | 31 (44.3%) | 8 (11.4%) | Â |
Double orphan | 6 (37.5%) | 3 (18.7%) | 4 (25%) | 3 (18.8%) | Â |
Both alive | 37 (42.5%) | 9 (10.4%) | 39 (44.8%) | 2 (2.3%) | 0.073 Ω |