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Table 2 Outcomes after 48 weeks of boosted protease inhibitor regimens

From: High virologic response rate after second-line boosted protease inhibitor-based antiretroviral therapy regimens in children from a resource limited setting

Outcomes Week 48
Total Single –boosted PI Double-boosted PI P-value
Median (IQR) CD4% 20 (15–26) (n = 200) 24 (18–30) (n = 83) 17 (14–22) (n = 117) < 0.001
Median(IQR) CD4% gain 10(1–7) (n = 199) 7(2–12) (n = 83) 10(6–15) (n = 116) 0.002
% with HIV RNA < 400 copies/ml 81.3 (n = 144) 83.1 (n = 65) 79.8 (n = 79) 0.610
% with HIV RNA < 50 copies/ml 63.0 (n = 138) 76.6 (n = 64) 51.4 (n = 74) 0.002
% with Cholesterol > 200 mg/dl 42.5 (n = 162) 34.3 (n = 70) 48.9 (n = 92) 0.062
% with Triglyceride > 150 mg/dl 62.4 (n = 157) 61.8 (n = 68) 62.9 (n = 89) 0.882
% with Low density lipoprotein > 130 mg/dl 31.8 (n = 88) 16.2 (n = 37) 43.1 (n = 51) 0.007