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Table 1 Comparison between rebounders and secondary controllers

From: Control of viral replication after cessation of HAART

  Rebounders (n = 66) Secondary controllers (n = 2)
   P1 P2
Sex:    
   Male 43 M F
   Female 23   
Age at start HAART (years) 37 (20-61)a 50 b 45
Clinical parameters of infection    
Days since diagnosis 4563 (1529-8469) 7709 4191
Days on HAART 1364 (160-4063) 4257 2860
Days off HAART 541 (182-2468) not restarted not restarted
CD4 at start HAART 292 (23-804) 228 377
CD4 at stop HAART 698 (113-1669) 458 1326
VL before start HAART 4.98 (3.47-6.0) 3.4
(under AZT)
4.6
(treatment naïve)
VL 6 months after stopping HAART 4.69 (3.04-6.0) <1.6 < 1.6
Months with undetectable VL under HAART 25 (1-98) 65 83
HIV-1 subtype    
  3 A B D
  17 B   
  1 D   
  2 H   
  3 CRF_01   
  4 CRF_02   
  1 CRF_36   
  1 CRF_D/F1   
  34 unknown   
Markers of immune activation    
sCD14 (ng/ml)    
T1 2066 (1682-2380)c ND 1648
T2 2032 (1627-2499) 3037 3119
T3 2173 (1744-2740) 4269 1760
LPS (EU/ml)    
T1 4.04 (3.02-6.45) ND 7.4
T2 4.17 (3.02-5.8) 3.41 3.36
T3 4.61 (3.41-5.35) 4.31 4.43
Neopterin (nmol/l)    
T1 8.15 (4.93-11.61) ND 13.14
T2 18.22 (11.36-25.07) 9.35 17.76
T3 8.75 (5.37-17.1) 5.16 15.03
Beta-2 microglobulin (μg/ml)    
T1 448 (346-596) ND 300
T2 252 (226-308) 336 212
T3 466 (344-566) 694 280
HLA types   B4101, B5201 B1402, B3501
  1. ND: not done, because no plasma sample was available
  2. T1 = before start of HAART; T2 = during HAART; T3 = 6 months after treatment cessation:
  3. a Rebounders: median (min-max)
  4. b For secondary controllers number is given
  5. c Rebounders: median (IQR)