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Table 2 Comparisons of clinical parameters to determine risk factors of virological failure among 788 HIV-infected patients

From: Incidence and risk factors of antiretroviral treatment failure in treatment-naïve HIV-infected patients at Chiang Mai University Hospital, Thailand

Variables

Univariate analysis

Multivariate analysis

 

Odds Ratio (95% CI)

P-value

Odds Ratio (95%CI)

P-value

Male vs. female

0.95 (0.65-1.69)

0.847

-

-

Age < 40 vs. ≥ 40 years

2.06 (1.23-3.46)

0.006

2.28 (1.22-4.25)

0.040

Heterosexual vs. non-heterosexual transmission

0.49 (0.20-1.23)

0.125

  

Urban vs. rural area

1.18 (0.66-2.10)

0.581

-

-

No health insurance vs. had health insurance

0.77 (0.23-2.57)

0.671

  

OIs before cART vs. no OIs before cART

0.84 (0.53-1.36)

0.488

-

-

Baseline CD4 cell count < 100 vs. ≥ 100 cells/mm3

1.56 (0.91-2.69)

0.106

-

-

Positive HCV antibody vs. negative HCV antibody

0.93 (0.35-2.44)

0.887

-

-

Positive HBs Ag vs. negative HBs antigen

1.25 (0.54-2.89)

0.603

-

-

Adherence < 95% vs. ≥ 95%

87.24 (32.29-235.72)

< 0.0001

86.49 (31.19-239.80)

< 0.001

  1. Abbreviations: OI, opportunistic infection; cART, combination antiretroviral therapy; HCV, hepatitis C virus; HBs Ag, hepatitis B surface antigen