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Table 2 Treatment outcomes during 96 weeks

From: Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children

Outcomes* Week 0
N = 107
Week 48
N = 103
Week 96
N = 98
p-value
Clinical outcomes     
Weight for age z-score -1.5(-2.4, -0.4) -1.1(-1.8,-0.6) -1.2(-2.0,-0.5) 0.014
Height for age z-score -1.7(-2.6, -1.1) -1.7(-2.3,-1.0) -1.4(-2.0,-0.6) <0.001
Weight for height z-score -0.5(-1.6, 0.3) -0.1(-0.6,0.5) -0.3(-1.2,0) >0.05
Laboratory outcomes     
Hemoglobin (g/dL) 10.6(9.5-11.7) 12.1(11.0-12.7) 12.1(11-12.7) <0.001
CD4% 7(3-15) 21(15-25) 25(18-30) <0.001
CD4 count (cells/mm3) 151(35-477) 531(367-811) 707(422-915) <0.001
Percent of children with immune recovery (%) 0 82.2 89.1  
Percent of children with HIV-RNA<1.7log10copies/ml (%) 0 69.1 75.0  
ALT (U/L) 27(16-46) 22(16-28.5) 22(17-28) 0.01
  1. Immune recovery was defined as recovery of CD4 to ≥ 25% after HAART initiation
  2. *Data was shown in median (IQR)