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Table 2 Treatment outcomes during 96 weeks

From: Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children

Outcomes*

Week 0

N = 107

Week 48

N = 103

Week 96

N = 98

p-value

Clinical outcomes

    

Weight for age z-score

-1.5(-2.4, -0.4)

-1.1(-1.8,-0.6)

-1.2(-2.0,-0.5)

0.014

Height for age z-score

-1.7(-2.6, -1.1)

-1.7(-2.3,-1.0)

-1.4(-2.0,-0.6)

<0.001

Weight for height z-score

-0.5(-1.6, 0.3)

-0.1(-0.6,0.5)

-0.3(-1.2,0)

>0.05

Laboratory outcomes

    

Hemoglobin (g/dL)

10.6(9.5-11.7)

12.1(11.0-12.7)

12.1(11-12.7)

<0.001

CD4%

7(3-15)

21(15-25)

25(18-30)

<0.001

CD4 count (cells/mm3)

151(35-477)

531(367-811)

707(422-915)

<0.001

Percent of children with immune recovery (%)

0

82.2

89.1

 

Percent of children with HIV-RNA<1.7log10copies/ml (%)

0

69.1

75.0

 

ALT (U/L)

27(16-46)

22(16-28.5)

22(17-28)

0.01

  1. Immune recovery was defined as recovery of CD4 to ≥ 25% after HAART initiation
  2. *Data was shown in median (IQR)