Outcomes* | Week 0 N = 107 | Week 48 N = 103 | Week 96 N = 98 | p-value |
---|---|---|---|---|
Clinical outcomes | Â | Â | Â | Â |
Weight for age z-score | -1.5(-2.4, -0.4) | -1.1(-1.8,-0.6) | -1.2(-2.0,-0.5) | 0.014 |
Height for age z-score | -1.7(-2.6, -1.1) | -1.7(-2.3,-1.0) | -1.4(-2.0,-0.6) | <0.001 |
Weight for height z-score | -0.5(-1.6, 0.3) | -0.1(-0.6,0.5) | -0.3(-1.2,0) | >0.05 |
Laboratory outcomes | Â | Â | Â | Â |
Hemoglobin (g/dL) | 10.6(9.5-11.7) | 12.1(11.0-12.7) | 12.1(11-12.7) | <0.001 |
CD4% | 7(3-15) | 21(15-25) | 25(18-30) | <0.001 |
CD4 count (cells/mm3) | 151(35-477) | 531(367-811) | 707(422-915) | <0.001 |
Percent of children with immune recovery (%) | 0 | 82.2 | 89.1 | Â |
Percent of children with HIV-RNA<1.7log10copies/ml (%) | 0 | 69.1 | 75.0 | Â |
ALT (U/L) | 27(16-46) | 22(16-28.5) | 22(17-28) | 0.01 |