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Table 3 Unadjusted and adjusted Cox regression models for baseline factors associated with time to death

From: Mortality in an antiretroviral therapy programme in Jinja, south-east Uganda: a prospective cohort study

Factor

Level

Unadjusted HR (95% c.i.)

Adjusted HR (95% c.i.)

Adjusted P-value

Sex

Male

1 (ref. level)

1 (ref. level)

0.002

 

Female

0.73 (0.52; 1.02)

0.59 (0.44; 0.80)

 

Study Arm

Facility

1 (ref. level)

1 (ref. level)

 
 

Home-based

1.003 (0.77; 1.31)

0.92 (0.70; 1.20)

0.56

Age

Per 10 year increase

1.002 (0.84; 1.20)

1.09 (0.91; 1.31)

0.30

WHO stage

I

0.58 (0.08; 4.0)

0.72 (0.12; 4.42)

0.009

 

II

1 (ref. level)

1 (ref. level)

 
 

III

1.99 (1.57; 2.53)

1.41 (1.09; 1.83)

 
 

IV

3.64 (2.53; 5.23)

2.23 (1.45; 3.43)

 

CD4/25

Per transformed CD4 increase *

0.52 (0.44; 0.61)

0.61 (0.51; 0.73)

< 0.001

Log10 plasma viral load

Per 1 log increase

1.15 (1.004; 1.31)

1.04 (0.91; 1.18)

0.51

Weight

Per 5 kg increase

0.74 (0.67; 0.82)

0.77 (0.70; 0.85)

< 0.001

Haemoglobin

Per 2 g/dl increase

0.82 (0.72; 0.93)

0.93 (0.81; 1.07)

0.35

Cotrimoxazole prophylaxis

Yes

No

1 (ref. level)

2.03 (1.08; 3.81)

1 (ref. level)

2.18 (1.10; 4.34)

0.02

  1. * Because of the CD4 count transformation, per unit increases here means an increase in CD4 count from 0 to 25, or from 25 to 100, or from 100 to 225 etc;