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Figure 6 | AIDS Research and Therapy

Figure 6

From: HIV-1 transgene expression in rats induces differential expression of tumor necrosis factor alpha and zinc transporters in the liver and the lung

Figure 6

Proposed hypothetical scheme: HIV-1 transgene and proteins cause hepatic inflammation and hepatic zinc sequestration resulting in pulmonary zinc deficiency, and decreased alveolar macrophage function. Dietary zinc supplementation modulates this vicious cycle and reduces pulmonary effects mediated by HIV-1 transgene and related proteins.

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