Figure 4
From: Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats
Gene levels of IL-6 super family members are differentially regulated in diseased plantaris muscles. As previously described [16], chronic alcohol ingestion induced expression of IL-6 (A) and LIF (B). The co-morbidity of twelve weeks of daily alcohol ingestion and HIV-1-related protein expression reduced gene expression of CT-1 (C) and CNTF (D). Data are represented as means ± range of potential values based on the 2-ΔΔCT method [15, 16] and expressed as fold changes relative to controls (n = 6-7 rats/group). Significance was accepted at p ≤ 0.05. *, compared to control-fed, otherwise-healthy rats. #, compared to control-fed, HIV-1 transgenic rats.