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Table 1 Summary of animal groups and disease outcomes

From: Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy

Animal ID

Age (yrs)*

Weight (kg)*

MHC type

Reason for death

Survival (months)

SIV

ART Treatment

ART nephropathy

Renal failure

3406

14.0

13.5

A02

nephropathy

4

yes

ART

likely

BUN 181, Ca/P 15.6/9.6, creatinine 23.3

3442

5.0

8.7

B01

open

11

no

-

n/a

n/a

3443

5.9

8.3

-

autolysis

14

yes

ART

unknown

unknown

3444

5.5

10.9

A01, B01

study ended/euthanized

18

yes

ART+DNA

yes

no biochemical evidence

3445

5.2

7.5

A08

open

2

yes

-

n/a

n/a

3446

7.3

9.3

A08

n/a

n/a

no

-

n/a

n/a

3447

6.3

11.5

A01, A08

study ended/euthanized

18

yes

ART

yes

no biochemical evidence

3448

5.4

5.7

-

nephropathy

4

yes

ART

likely

BUN 113, Ca/P12.9/4.8, creatinine 6.4

3449

6.6

13.8

A08

study ended/euthanized

18

yes

ART+DNA+IL-2

yes

no biochemical evidence

3451

8.6

10.0

-

study ended/euthanized

18

yes

ART

yes

no biochemical evidence

3452

7.5

9.3

A08

study ended/euthanized

18

yes

ART

yes

no biochemical evidence

3453

6.8

8.8

-

study ended/euthanized

18

yes

ART

no

no biochemical evidence

3511

5.4

9.2

A01

study ended/euthanized

20

yes

ART

no

no biochemical evidence

3512

5.3

6.7

A02

granulomatous hepatitis

17

yes

ART+DNA+IL-2

no

no biochemical evidence

3514

5.3

9.0

A01, A08, B01

study ended/euthanized

19

yes

ART+DNA+IL-2

yes

no biochemical evidence

3515

5.4

10.2

A01

study ended/euthanized

19

yes

ART

yes

no biochemical evidence

3516

5.4

10.1

A01, A08

study ended/euthanized

19

yes

ART+DNA+IL-2

yes

no biochemical evidence

3517

4.7

5.2

-

poor viral control

10

yes

ART

unknown

no biochemical evidence

3518

5.4

8.9

-

study ended/euthanized

19

yes

ART+DNA+IL-2

yes

no biochemical evidence

3519

5.4

7.4

A02, A08, B01

study ended/euthanized

18

yes

ART

no

no biochemical evidence

3520

4.6

4.4

A08, B01

poor viral control

10

yes

ART

unknown

no biochemical evidence

3521

4.7

5.9

A01, B01

poor viral control

10

yes

ART

unknown

no biochemical evidence

3522

5.5

7.2

A01

study ended/euthanized

20

yes

ART+DNA

no

no biochemical evidence

3523

5.2

6.9

A08

SIVE/Pneumonia

17

yes

ART

no

no biochemical evidence

3524

5.5

9.2

A01

study ended/euthanized

19

yes

ART+DNA

yes

no biochemical evidence

3525

5.4

8.3

A01, B01

study ended/euthanized

19

yes

ART+DNA+IL-2

no

no biochemical evidence

3526

5.7

6.5

A08, B01

study ended/euthanized

20

yes

ART+DNA

no

no biochemical evidence

3527

5.7

10.7

A08

study ended/euthanized

20

yes

ART+DNA

no

no biochemical evidence

3528

4.6

5.5

A01, B01

diseased

5

yes

ART

unknown

no biochemical evidence

3529

4.4

5.1

A08

open

3

yes

-

n/a

n/a

3530

5.3

10.7

A02, B01

study ended/euthanized

19

yes

ART+DNA

yes

no biochemical evidence

3680

8.8

14.4

B01

n/a

n/a

no

-

n/a

n/a

3684

6.2

10.9

B01

pneumonia

14

yes

ART

yes

no biochemical evidence

  1. *at study end