Skip to main content

Advertisement

Table 3 Bivariate analyses displaying predictors of Hepatitis C therapy in HIV co-infected patients

From: Reliability and predictive validity of a hepatitis-related symptom inventory in HIV-infected individuals referred for Hepatitis C treatment

Variable HCV treatment subset P Value
  No (n = 94) Yes (n = 32)  
Gender:    
   Female 14 7 0.56
   Male 79 25  
Race/ethnicity:    
   White 55 11 0.09
   Hispanic 20 9  
   Black 17 10  
   Unknown/other 2 2  
Race/ethnicity, dichotomized:    
   White 55 11 0.02
   Non-white 39 21  
HIV risk factor:    
   Gay/bisexual 34 13 0.96
   Heterosexual 11 3  
   Intravenous drug use 39 13  
   Hemophiliac 1 0  
   Unknown/other 0 3  
CD4 cell count (×106/l), mean (sd) 488(294) 478(272) 0.61
HIV log10 viral load, mean(sd) 2.12(0.96) 1.66(0.07) 0.01
HCV log10 RNA, mean (sd) 6.36(1.30) 6.27(1.12) 0.63
HCV genotype:    
   Genotype 2 & 3 14 6 0.65
   Genotype 1 & 4 74 25  
History of neuropsychiatric disease (%) 56 (60) 18 (56) 0.74
Ever use illicit substance (%) 87 (93) 28 (88) 0.38
Ongoing illicit substance use (%) 12 (13) 3 (9) 0.61
Total symptoms score, mean (sd) 73(25) 56(10) 0.002
Neuropsychiatric symptoms score, mean(sd) 28(11) 19(4) 0.00006
Somatic symptoms score, mean (sd) 19(8) 16(5) 0.0001
Sleep symptoms score, mean (sd) 4(3) 3(2) 0.04
CES-D score, mean (sd) 17(13) 8(7) 0.00003
  1. CES-D = Center for Epidemiologic Studies Depression Scale.