Skip to main content

Advertisement

Table 4 Hazard Ratios for pathways between known resistance locations

From: HIV-1 mutational pathways under multidrug therapy

Hazard ratios between known resistance locations
Pathway Hazard Confidence Bounds
41 → 108 7.54 (2.2, 25.8)
67 → 70 3.52 (2.08, 5.98)
67 → 190 3.19 (1.41, 7.21)
67 → 219 2.97 (1.72, 5.14)
70 → 210* 0.33 (0.15, 0.75)
70 → 219 2.68 (1.6, 4.47)
74 → 100 12.92 (3.48, 47.95)
77 → 103 7.76 (2.6, 23.16)
115 → 106 17.51 (1.26, 243.88)
116 → 62 27.81 (8.73, 88.58)
151 → 116 237.67 (34.71, 1627.63)
181 → 65 3.28 (1.22, 8.81)
184 → 181 1.77 (1.07, 2.92)
184 → 210 0.27 (0.17, 0.42)
190 → 184 1.84 (1.15, 2.95)
210 → 70 0.09 (0.03, 0.23)
215 → 41 3.23 (2.15, 4.85)
215 → 65 0.06 (0.01, 0.28)
  1. Estimated hazard ratios and 95% confidence bounds for all pathways between known resistance locations with p < 0.01. Two additional pathways, which were remarked on in the text, are also included. Estimation was done using the survival [24] package of the R software environment [22].
  2. *p = 0.011 p= 0.019