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Table 2 Univariate and multivariable Cox proportional hazard models of baseline characteristics and risk of pre-treatment mortality in ART-eligible patients.

From: Pre-treatment mortality and loss-to-follow-up in HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients eligible for antiretroviral therapy in The Gambia, West Africa

  

Univariate analysis

Multivariable analysisФ

  

Hazard ratio for death (95% CI)

P

Hazard ratio for death (95% CI)

P

Sex: (n = 789)

     

Male

251 (31.8%)

1.49 (1.03, 2.15)

0.036

1.40 (0.95, 2.07)

0.092

Female

538 (68.2%)

1.0

 

1.0

 

Age: (n = 789)

     

<30

185 (23.5%)

1.0

 

1.0

 

30 - 40

327 (41.4%)

1.10(0.68, 1.78)

 

1.19 (0.72, 1.98)

 

>40

277 (35.1%)

1.09 (0.67, 1.80)

0.914

1.15 (0.67, 1.95)

0.784

HIV type: (n = 789)

    

HIV-1

647 (82.0%)

1.0

   

HIV-2

103 (13.1%)

0.73 (0.42, 1.26)

 

-

 

HIV-dual

39 (4.9%)

1.07 (0.49, 2.31)

0.484

  

CD4 count: (n = 787)

    

<100

258 (32.8%)

3.69 (2.55, 5.35)

<0.001

3.71 (2.54, 5.41)

<0.001

≥100

529 (67.2%)

1.0

 

1.0

 

Occupation: (n = 476)

    

Employed

260 (54.6%)

1.0

   

Unemployed

216 (45.4%)

0.61 (0.37, 1.02)

0.068

-

 

WHO stage: (n = 722)

    

1 or 2

657 (91.0%)

1.0

 

1.0

 

3 or 4

65 (9.0%)

2.13 (1.30, 3.49)

0.006

1.91 (1.12, 3.23)

0.017

  1. ¶ Proportional hazard assumption is valid in all univariate and the multivariable Cox proportional hazard models.
  2. Ф Adjusting for Sex, Age, CD4 count category and WHO stage. Occupation was not included in the multivariable model because it was not significant in the univariate analysis; neither does it change the model significantly.
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AIDS Research and Therapy

ISSN: 1742-6405

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