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Table 2 Epidemiological and demographic characteristics of children, and bivariate analysis of factors associated with first event of opportunistic illnesses

From: Opportunistic illnesses in Brazilian children with AIDS: results from two national cohort studies, 1983-2007

  

Total

N (%)

Opportunistic illness

N (%)

OR

(95% CI)

p

Total

-

1859 (100.0)

1218 (65.5%)

-

-

Study cohort

1983-1998

914 (49.2)

738 (80.7)

ref

 
 

1999-2002

945 (50.8)

480 (50.8)

0.25 (0.20-0.30)

< 0.001

Brazilian region (residence)

North

107 (5.8)

23 (21.5)

ref

 
 

Northeast

288 (15.5)

122 (42.4)

2.68 (1.62-4.46)

< 0.001

 

Southeast

931 (50.1)

704 (75.6)

11.33 (7.51-17.09)

< 0.001

 

South

395 (21.2)

267 (67.6)

7.62 (4.78-12.13)

< 0.001

 

Central-West

138 (87.4)

102 (73.9)

10.35 (5.89-18.18)

< 0.001

Gender

Male

909 (48.9)

594 (65.3)

ref

 
 

Female

950 (51.1)

624 (65.7)

1.02 (0.84-1.23)

0.88

Birth cohort

< 1988

155 (8.3)

127 (81.9)

ref

 
 

1989-1995

819 (44.1)

582 (71.1)

0.54 (0.35-0.83)

0.006

 

1996-2002

885 (47.6)

509 (57.5)

0.30 (0.20-0.45)

< 0.001

Age Group, HIV diagnosis

< 1 year

667 (35.9)

515 (77.2)

2.56 (1.81-3.61)

< 0.001

 

1-5 years

1020 (54.9)

605 (59.3)

1.10 (0.79-1.53)

0.62

 

6-12 years

172 (9.3)

98 (57.0)

ref

 

Year, HIV diagnosis

< 1988

35 (1.9)

28 (80.0)

ref

 
 

1989-1995

544 (29.3)

449 (82.5)

1.18 (0.50-2.78)

0.65

 

1996-2002

1280 (68.9)

741 (57.9)

0.34 (0.15-0.76)

0.009

ART use

Yes

1555 (83.6)

990 (63.7)

0.58 (0.44-0.77)

< 0.001

 

No

304 (16.4)

228 (75.0)

ref

 

Year, ART initiation

< 1996

314 (20.2)

259 (82.5)

ref

 
 

1996-2002

1241 (79.8)

731 (58.9)

0.30 (0.23-0.41)

< 0.001

Children status

Alive

1226 (68.9)

695 (56.7)

0.26 (0.20-0.33)

< 0.001

 

Dead

554 (31.1)

463 (83.6)

ref

 

Prenatal care

Yes

818 (76.6)

533 (65.2)

1.07 (0.80-1.44)

0.65

 

No

250 (23.4)

159 (63.6)

ref

 

Breast-feeding

Yes

969 (78.7)

628 (64.8)

0.92 (0.69-1.22)

0.56

 

No

262 (21.3)

175 (66.8)

ref

 

MTCT prophylaxis

Yes

254 (15.3)

139 (54.7)

ref

 
 

No

1404 (84.7)

922 (65.7)

1.58 (1.21-2.07)

0.001