|  | Total N (%) | Opportunistic illness N (%) | OR (95% CI) | p |
---|---|---|---|---|---|
Total | - | 1859 (100.0) | 1218 (65.5%) | - | - |
Study cohort | 1983-1998 | 914 (49.2) | 738 (80.7) | ref | Â |
 | 1999-2002 | 945 (50.8) | 480 (50.8) | 0.25 (0.20-0.30) | < 0.001 |
Brazilian region (residence) | North | 107 (5.8) | 23 (21.5) | ref | Â |
 | Northeast | 288 (15.5) | 122 (42.4) | 2.68 (1.62-4.46) | < 0.001 |
 | Southeast | 931 (50.1) | 704 (75.6) | 11.33 (7.51-17.09) | < 0.001 |
 | South | 395 (21.2) | 267 (67.6) | 7.62 (4.78-12.13) | < 0.001 |
 | Central-West | 138 (87.4) | 102 (73.9) | 10.35 (5.89-18.18) | < 0.001 |
Gender | Male | 909 (48.9) | 594 (65.3) | ref | Â |
 | Female | 950 (51.1) | 624 (65.7) | 1.02 (0.84-1.23) | 0.88 |
Birth cohort | < 1988 | 155 (8.3) | 127 (81.9) | ref | Â |
 | 1989-1995 | 819 (44.1) | 582 (71.1) | 0.54 (0.35-0.83) | 0.006 |
 | 1996-2002 | 885 (47.6) | 509 (57.5) | 0.30 (0.20-0.45) | < 0.001 |
Age Group, HIV diagnosis | < 1 year | 667 (35.9) | 515 (77.2) | 2.56 (1.81-3.61) | < 0.001 |
 | 1-5 years | 1020 (54.9) | 605 (59.3) | 1.10 (0.79-1.53) | 0.62 |
 | 6-12 years | 172 (9.3) | 98 (57.0) | ref |  |
Year, HIV diagnosis | < 1988 | 35 (1.9) | 28 (80.0) | ref | Â |
 | 1989-1995 | 544 (29.3) | 449 (82.5) | 1.18 (0.50-2.78) | 0.65 |
 | 1996-2002 | 1280 (68.9) | 741 (57.9) | 0.34 (0.15-0.76) | 0.009 |
ART use | Yes | 1555 (83.6) | 990 (63.7) | 0.58 (0.44-0.77) | < 0.001 |
 | No | 304 (16.4) | 228 (75.0) | ref |  |
Year, ART initiation | < 1996 | 314 (20.2) | 259 (82.5) | ref | Â |
 | 1996-2002 | 1241 (79.8) | 731 (58.9) | 0.30 (0.23-0.41) | < 0.001 |
Children status | Alive | 1226 (68.9) | 695 (56.7) | 0.26 (0.20-0.33) | < 0.001 |
 | Dead | 554 (31.1) | 463 (83.6) | ref |  |
Prenatal care | Yes | 818 (76.6) | 533 (65.2) | 1.07 (0.80-1.44) | 0.65 |
 | No | 250 (23.4) | 159 (63.6) | ref |  |
Breast-feeding | Yes | 969 (78.7) | 628 (64.8) | 0.92 (0.69-1.22) | 0.56 |
 | No | 262 (21.3) | 175 (66.8) | ref |  |
MTCT prophylaxis | Yes | 254 (15.3) | 139 (54.7) | ref | Â |
 | No | 1404 (84.7) | 922 (65.7) | 1.58 (1.21-2.07) | 0.001 |