Figure 1

The effect of intravenous immunoglobulin (IVIG) on plasma HIV-1 RNA. Rebound of plasma HIV-1 RNA to pre-treatment levels at follow-up after initial decrease 8-12 weeks after treatment with IVIG. At follow-up six out of nine patients had detectable levels of plasma HIV-1 RNA (median < 2 copies/mL, IQR < 2-12 copies/mL, mean 8 copies/mL ± SD 12.8) compared to one patient 8-12 weeks after IVIG treatment (median < 2 copies/mL, IQR < 2 copies/mL, mean 1.7 copies/mL SD ± 2.3). No difference in plasma HIV-1 RNA between treated (median < 2 copies/mL IQR < 2-12 copies/mL, mean 8 copies/mL SD ± 12.8) and controls (median < 2 copies/mL, IQR < 2-7.25 copies/mL, mean 5.7 copies/mL SD ± 8.9) at follow-up.

Quantitative detection limit (2 copies/mL) is marked by grid line.