From: Long-term CD4+ lymphocyte response following HAART initiation in a U.S. Military prospective cohort
Covariate | Estimate (95% CI) | P-value |
---|---|---|
Age at HAART start | Â | Â |
   Effect of 10 years older if < 40 years old | 6.3 (-9.6, 22.2) | 0.44 |
   Effect of 10 years older if > 40 years old | - 5.1 (-23.9, 13.7) | 0.59 |
Female (vs. Male) | 57.2 (14.6, 99.8) | 0.009 |
Race | Â | Â |
   Caucasian | Reference |  |
   African American | 9.2 (-7.3, 25.7) | 0.27 |
   Hispanic | -10.8 (-38.6, 17.1) | 0.45 |
   Other | 0.4 (-40.6, 41.4) | 0.98 |
Clinical AIDS event prior to HAART start | -32.7 (-66.4, 1.0) | 0.057 |
Pre -HAART nadir CD4 count (cells/mm3) | Â | Â |
≤ 200 | Reference |  |
201-349 | 55.3 (20.7, 89.9) | 0.002 |
350-499 | 135.4 (94.6, 176.2) | <.001 |
≥ 500 | 195.1 (144.3, 245.8) | <.001 |
Baseline VL at HAART start (copies/ml) ** | Â | Â |
< 1000 | 8.5 (-21.6, 38.6) | 0.58 |
1000-9999 | -17.8 (-43.5, 7.9) | 0.18 |
10,000-99,999 | 1.3 (-19.5, 22.2) | 0.90 |
≥ 100,000 | Reference |  |
Years from SC to HAART initiation | Â | Â |
   ≤ 1.5 | Reference |  |
   > 1.5 to 4.0 | -18.0 (-38.6, 2.6) | 0.09 |
   > 4.0 to 8.5 | -27.7 (-52.0, -3.3) | 0.03 |
   ≥ 8.5 | -33.4 (-61.0, -5.8) | 0.02 |
Year of HAART initiation | Â | Â |
   1995-1999 | 0.0 (-22.4, 22.4) | 0.99 |
   2000-2003 | 5.9 (-18.1, 29.9) | 0.63 |
   2004-2009 | Reference |  |
Any ART prior to HAART start | 11.5 (-11.1, 34.0) | 0.32 |