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Table 1 Baseline subject characteristics

From: Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot study

  Median Range
Age (years) 49.9 32.0 - 55.2
Gender (M:F) 6:1  
Time since HIV diagnosis (years) 17.0 1.7 - 20.3
HIV-1 RNA (log10 copies/mL)   
   Plasma 4.49 4.26 - 5.56
   CSF 3.87 3.11 - 4.47
   Plasma:CSF difference 1.06 0.12 - 1.58
Blood T cells (cells/μL)   
   CD4+ 453 267 - 806
   CD8+ 1,009 575 - 2185
CSF WBCs (cells/μL) 9 2 - 18
Neopterin (nmol/L)   
   CSF 13.1 5.9 - 41.2
   Plasma 13.4 9.2 - 53.5
CSF CCL2 (pg/mL) 479.2 397.9 - 1322.2
T Cell Activation (percent CD38+/HLA-DR+)  
   CSF CD4+ 14.7 3.4 - 60.2
   Blood CD4+ 13.3 7.6 - 24.7
   CSF CD8+ 83.4 41.8 - 97.6
   Blood CD8+ 58.5 34.5 - 78.0
Monocyte Activation (percent CD16+)  
   CSF monocytes 93.6 80.1 - 100
   Blood monocytes 10.8 4.7 - 17.0
CSF:blood albumin ratio 5.05 3.91 - 12.26
QNPZ-4 -0.32 -3.44 - 0.54