Table 4 Demographic and laboratory parameters stratified to risk category based on hsCRP levels
| Â | Low risk category (hsCRP < 1 mg/L) | Average risk category (hsCRP 1-3 mg/L) | High risk category (hsCRP >3 mg/L) |
|---|---|---|---|
Number of patients | 28 | 24 | 27 |
Age (years) | 47.8 (± 10.2) | 48.4 (± 11.6) | 48.2 (± 9.1) |
Duration of cART use (months) | 76 (25-125) | 116 (42-124) | 111 (26-127) |
CD4 cell count (cells/mm3) | 390 (300-765) | 460 (340-805) | 500 (288-633) |
HIV viral load <40 copies/ml (%) | 24 (86) | 21 (88) | 22 (81) |
Total cholesterol (mmol/L) | 4.9 (± 1.0) | 5.7 (± 0.9) | 5.1 (± 0.8) |
Triglycerides (mmol/L) | 2.2 (± 1.9) | 2.7 (± 2.0) | 2.0 (± 1.4) |
Non-fasting glucose (mmol/L) | 5.9 (± 1.1) | 5.9 (± 1.1) | 6.1 (± 1.6) |
Patients on ABC (%) | 9 (32) | 7 (29) | 11 (41) |
aPTT (sec) | 31.5 (± 3.3) | 32.2 (± 3.1) | 30.5 (± 3.2) |
PT (sec) | 11.8 (± 0.9) | 11.7 (± 0.6) | 11.5 (± 0.8) |
Fibrinogen (g/L) | 2.4 (2.1-2.6) | 2.8 (2.3-3.2)* | 3.5 (2.8-4.1)* |
FVIII (%) | 115 (102-145) | 122 (105-172) | 122 (100-158) |
vWF (%) | 124 (92-160) | 123 (101-177) | 114 (98-188) |
D-dimer (mg/L) | 0.2 (0.2-0.3) | 0.2 (0.2-0.3) | 0.3 (0.2-0.5)* |
F1+2 (pmol/L) | 175 (151-229) | 210 (163-269) | 219 (197-305)* |
PC (%) | 114 (± 25.7) | 111 (± 20.6) | 120 (± 20.9) |
PS total (%) | 96 (± 18.7) | 104 (± 14.5) | 105 (± 20.8) |
PS free (%) | 87 (± 16.8) | 93 (± 24.8) | 82 (± 26.0) |
ETP (nM.min) | 1663 (± 274) | 1803 (± 237)* | 1913 (± 336)* |
ETP peak (nM) | 371 (328-401) | 371 (341-407) | 386 (364-417) |
APCsr | 2.9 (2.1-3.7) | 2.0 (1.7-2.9)* | 2.6 (1.6-4.4) |
VEGF (pg/ml) | 30 (24-42) | 30 (26-52) | 37 (27-53) |
IL-6 (pg/ml) | 1.0 (-) | 1.0 (-) | 1.0 (-) |