Table 1 Amino acid positions outside RT codon 41-238 contributing to the HIVDR interpretation algorithms. ROI: region of interest
ROI | ARV drugs | Stanford | virco®TYPE |
|---|---|---|---|
RT codon 1-40 | 3TC | none | 7, 8, 13, 35, 36, 40 (n = 6) |
ABC | none | 3, 13, 21, 33, 35, 39, 40 (n = 7) | |
AZT | none | none | |
d4T | none | 3, 13, 33, 35, 36, 40 (n = 6) | |
ddI | none | 3, 4, 33, 35, 36, 39, 40 (n = 7) | |
TDF | none | 4, 7, 13, 21, 33, 40 (n = 6) | |
EFV | none | 16, 20, 22, 27, 28, 31, 33, 34 (n = 8) | |
NVP | none | 21, 31, 35 (n = 3) | |
RT codon 239-400 | 3TC | none | 240, 248, 277, 313 (n = 4) |
ABC | none | 334, 348 (n = 2) | |
AZT | 333 (n = 1) | 240, 242, 244, 245, 282, 296, 297, 313, 334, 335, 350, 357, 359, 360, 375, 377, 386, 395 (n = 18) | |
d4T | none | 334, 348, 357, 359 (n = 4) | |
ddI | none | 348, 359, 360, 395 (n = 4) | |
TDF | none | 242, 245, 249, 277, 297, 329, 334, 335, 353, 357, 359, 395 (n = 12) | |
EFV | 318 (n = 1) | 240, 241, 243, 244, 245, 250, 251, 257, 271, 272, 274, 282, 283, 286, 292, 297, 313, 317, 318, 329, 333, 334, 335, 338, 339, 348, 353, 356, 357, 358, 365, 366, 369, 370, 371, 375, 376, 377, 379, 381, 382, 385, 386, 390, 393, 394, 395, 400 (n = 48) | |
NVP | 318 (n = 1) | 244, 245, 248, 250, 272, 283, 286, 293, 297, 313, 317, 318, 329, 333, 334, 335, 338, 339, 348, 353, 356, 357, 358, 365, 366, 369, 370, 371, 374, 375, 376, 377, 379, 382, 385, 386, 390, 393, 394, 395, 399, 400 (n = 42) |