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Table 3 Results of applying the logistic model to both the training set and validation set using a predicted probability of 0.5 as the cutoff*.

From: Identifying individuals with virologic failure after initiating effective antiretroviral therapy: The surprising value of mean corpuscular hemoglobin in a cross-sectional study

Training Set (N = 784)

Model Classification*

HIV RNA > 500 copies/ml

HIV RNA ≤ 500 copies/ml

 

HIV RNA > 500 copies/ml

192

57

PPV = 0.77

HIV RNA ≤ 500 copies/ml

83

452

NPV = 0.84

 

Sensitivity 0.70 (95% CI: 0.64, 0.75)

Specificity 0.89 (95% CI: 0.86, 0.91)

 

Validation Set (N = 784)

Model Classification*

HIV RNA > 500 copies/ml

HIV RNA ≤ 500 copies/ml

 

HIV RNA > 500 copies/ml

205

57

PPV = 0.78

HIV RNA ≤ 500 copies/ml

71

451

NPV = 0.86

 

Sensitivity 0.74 (95% CI: 0.69, 0.79)

Specificity 0.89 (95% CI: 0.86, 0.91)

 
  1. * Individuals with probability >0.5 were classified as having HIV RNA > 500; Positive predictive value (PPV); Negative predictive value (NPV)