Table 1 HIV prevalence and incidence of women participating in trials in KwaZulu-Natal, and overall trial outcome.
Trial (total enrolment) | Years | Location of HPRU sites (no. enrolled) | HIV prevalence (%) | HIV incidence (/100 woman years) | Overall outcome of trial: HR (95% CI) |
|---|---|---|---|---|---|
MIRA (5045) | 2003-2006 | Durban (1515) | 39 | 6.8 | 1.05 (0.84-1.32) P = 0.65 |
Carraguard (6202) | 2004-2007 | Durban (1485) | 43 | 6 | 0.87 (0.69-1.09) P = 0.302 |
Cellulose sulphate (1428) | 2006-2007 | Durban (606) | 51 | 5.29 | 1.61 (0.86-3.01) P = 0.13 |
HPTN 035 (3101) | 2005-2008 | Durban (702) Hlabisa (346) | 21.6 28.2 | 4.6 9.1 | 0.71 (0.46-1.11) P = 0.1331 |
MDP 301 (9385) | 2005-2009 | Durban (2392) | 36 | 6.1 | 1.05 (0.82-1.34) P = 0.712 |