Skip to main content

Table 4 Patient characteristics associated with pharmacy non-adherence during the first 6 months after initiating ART

From: Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon

Characteristics

Best-case scenario

Worst-case scenario

 

OR (95%CI)

P-value

OR (95%CI)

P-value

Age (years)

 

0.09

 

0.95

<30

1.45 (0.74-2.83)

 

1.05 (0.57-1.95)

 

30-49

1

 

1

 

≥ 50

0.38 (0.11-1.33)

 

0.90 (0.40-2.04)

 

Sex

 

0.17

 

0.05

Male

1

 

1

 

Female

0.66 (0.37-1.18)

 

0.60 (0.35-1.01)

 

Monthly income (US$)

 

0.01

 

0.08

< USD 50 (20'000 FCFA)

2.49 (1.03-6.01)

 

1.73 (0.89-3.38)

 

USD 50 - USD125 (20'000-50'000)

1

 

1

 

> USD 125 (>50'000)

3.76 (1.47-9.58)

 

2.27 (1.08-4.77)

 

Education

 

0.82

 

0.16

Primary

1

 

1

 

Secondary without Bachelor

0.96 (0.51-1.83)

 

1.35 (0.76-2.37)

 

Secondary with Bachelor or University

0.74 (0.28-1.95)

 

0.64 (0.27-1.54)

 

Travel time to clinic (hour)

 

0.21

 

0.73

<1

1

 

1

 

1-4

0.88 (0.44-1.78)

 

1.24 (0.68-2.61)

 

>4

0.22 (0.03-1.74)

 

1.29 (0.44-3.79)

 

Baseline CD4-cell count (cells/μl)

 

0.75

 

0.85

<100

1.09 (0.62-1.93)

 

1.05 (0.64-1.73)

 

≥ 100

1

 

1

 

Clinical stage

 

0.44

 

0.001

CDC stage A

1

 

1

 

CDC stage B

1.60 (0.72-3.55)

 

2.68 (1.26-5.68)

 

CDC stage C

1.72 (0.62-4.75)

 

5.13 (2.02-13.0)

 

Initial ART regimen

    

Twice daily

1

0.81

1

0.79

Three times daily

0.93 (0.53-1.64)

 

1.07 (0.65-1.75)

 

Occurrence of ART side-effects at 1 month

 

0.46

 

0.64

No side-effects

1

 

1

 

One or more side-effects

0.74 (0.34-1.62)

 

0.84 (0.41-1.73)

 

Course of ART side-effects at 1 month

 

0.09

 

0.04

Improving

0.51 (0.23-1.10)

 

0.47 (0.24-0.95)

 

Not improving

1

 

1

 

Reported ART adherence at 1 month

    

100%

1

0.55

1

0.19

<100%

1.30 (0.56-3.01)

 

1.66 (0.78-3.52)

 

Disclosure of HIV status

 

0.82

 

0.38

Yes

1

 

1

 

No

0.98 (0.81-1.18)

 

1.07 (0.92-1.24)

 
  1. Non-adherent patients are compared with adherent patients in a best and a worst case scenario (best-case scenario: patients lost to follow-up were considered adherent; worst-case scenario: patients lost to follow-up were considered non-adherent). The associations of each characteristic with time stayed adherent were examined using logistic regression models.
Back to article page

AIDS Research and Therapy

ISSN: 1742-6405

Contact us