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Table 4 Patient characteristics associated with pharmacy non-adherence during the first 6 months after initiating ART

From: Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon

Characteristics Best-case scenario Worst-case scenario
  OR (95%CI) P-value OR (95%CI) P-value
Age (years)   0.09   0.95
<30 1.45 (0.74-2.83)   1.05 (0.57-1.95)  
30-49 1   1  
≥ 50 0.38 (0.11-1.33)   0.90 (0.40-2.04)  
Sex   0.17   0.05
Male 1   1  
Female 0.66 (0.37-1.18)   0.60 (0.35-1.01)  
Monthly income (US$)   0.01   0.08
< USD 50 (20'000 FCFA) 2.49 (1.03-6.01)   1.73 (0.89-3.38)  
USD 50 - USD125 (20'000-50'000) 1   1  
> USD 125 (>50'000) 3.76 (1.47-9.58)   2.27 (1.08-4.77)  
Education   0.82   0.16
Primary 1   1  
Secondary without Bachelor 0.96 (0.51-1.83)   1.35 (0.76-2.37)  
Secondary with Bachelor or University 0.74 (0.28-1.95)   0.64 (0.27-1.54)  
Travel time to clinic (hour)   0.21   0.73
<1 1   1  
1-4 0.88 (0.44-1.78)   1.24 (0.68-2.61)  
>4 0.22 (0.03-1.74)   1.29 (0.44-3.79)  
Baseline CD4-cell count (cells/μl)   0.75   0.85
<100 1.09 (0.62-1.93)   1.05 (0.64-1.73)  
≥ 100 1   1  
Clinical stage   0.44   0.001
CDC stage A 1   1  
CDC stage B 1.60 (0.72-3.55)   2.68 (1.26-5.68)  
CDC stage C 1.72 (0.62-4.75)   5.13 (2.02-13.0)  
Initial ART regimen     
Twice daily 1 0.81 1 0.79
Three times daily 0.93 (0.53-1.64)   1.07 (0.65-1.75)  
Occurrence of ART side-effects at 1 month   0.46   0.64
No side-effects 1   1  
One or more side-effects 0.74 (0.34-1.62)   0.84 (0.41-1.73)  
Course of ART side-effects at 1 month   0.09   0.04
Improving 0.51 (0.23-1.10)   0.47 (0.24-0.95)  
Not improving 1   1  
Reported ART adherence at 1 month     
100% 1 0.55 1 0.19
<100% 1.30 (0.56-3.01)   1.66 (0.78-3.52)  
Disclosure of HIV status   0.82   0.38
Yes 1   1  
No 0.98 (0.81-1.18)   1.07 (0.92-1.24)  
  1. Non-adherent patients are compared with adherent patients in a best and a worst case scenario (best-case scenario: patients lost to follow-up were considered adherent; worst-case scenario: patients lost to follow-up were considered non-adherent). The associations of each characteristic with time stayed adherent were examined using logistic regression models.