Figure 2From: Protease inhibitor-induced nausea and vomiting is attenuated by a peripherally acting, opioid-receptor antagonist in a rat modelDose-related effects of pretreatment with ritonavir on kaolin intake. Rats treated with saline only consumed < 1.0 g/day of kaolin during 5 consecutive days (0, 24, 48, 72, 96, and 120 hr). Ritonavir doses at 10 and 20 mg/kg significantly increased kaolin consumption at 24 to 48 hr in a dose-related manner (P < 0.01). Data are presented as mean ± SEM. n = 6 per group.Back to article page