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Figure 5 | AIDS Research and Therapy

Figure 5

From: The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT

Figure 5

Comparison between the ICS and two independently performed ELISPOT assays. The two ICS data evaluation systems are compared with ELISPOT assays performed by laboratory 1 (A) and laboratory 2 (B). Correlations between frequencies of responding T-cells detected by ELISPOT and by ICS using the IFN-γ+ MIP-1β+ or the total IFN-γ+ data evaluation system are determined by Spearman's rank correlation. r and p values are shown in each graph. 2 × 2 contingency tables comparing the positive T-cell responses detected by ELISPOT and by ICS with the two data evaluation systems are also shown.

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