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Figure 1 | AIDS Research and Therapy

Figure 1

From: The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT

Figure 1

IFN-γ and MIP1-β expression in CD8 and CD4 T-cells stimulated with HIV-1-derived antigens. Percentages of IFN-γ+ MIP-1β- and IFN-γ+ MIP-1β+ CD8 (A) or CD4 (C) T-cells are shown for a total of 275 samples. The mean is depicted for each T-cell population. Representative pseudo-colour dot plots of data gated on living CD8+ CD3+ lymphocytes (B) or living CD4+ CD3+ lymphocytes (D) from 4 different patients are shown. In each plot the percentage of IFN-γ+ MIP-1β-, IFN-γ+ MIP-1β+ and IFN-γ- MIP-1β+ is indicated in the bottom-right corner. The pools used for PBMC stimulation are described in Table 1. TL10, TPGPGVRYPL.

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