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Table 1 Chromosomal integration of different SB constructs.

From: Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance

Cell Line

SB Construct

Chromosomal Location

GHOST-R3/X4/R5

RFP control

Ch 5q34-q35, Ch 17q25.1

 

CXCR4 siRNA

Ch 17q23.3

 

CCR5 siRNA

Ch 5q34-q35.1, Ch 20q13.2

MAGI-CXCR4

RFP control

Ch 6p22.3, Ch 12q14.2

 

CXCR4 siRNA

Ch 5q33.1, Ch 7q31.1

MAGI-CCR5

RFP control

Ch 10p12.31, Ch 15q11

 

CCR5 siRNA

Ch 12p11.2, Ch 20q13.3