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Table 1 Metabolic parameters of LDL-R null mice treated with ritonavir.

From: Gender-specific effects of HIV protease inhibitors on body mass in mice

 

Male

Female

 

Vehicle

Ritonavir

Vehicle

Ritonavir

Total Cholesterol (mg/ml)

1.32 +/- 0.06

1.23 +/- 0.11

0.96 +/- 0.06*

0.98 +/- 0.08*

Insulin (ng/ml)

0.80 +/- 0.01

0.73 +/- 0.01

0.80 +/- 0.08

0.72 +/- 0.02

Glucose (mg/dL)

180.17 +/- 17.6

176.67 +/- 14.5

155.17 +/- 6.4

149.00 +/- 8.2

Estradiol (pg/ml)

ND

ND

9.19 +/- 1.8

12.75 +/- 2.3

  1. * = significantly different from male mice (p < 0.05)
  2. ND = Not Determined