Table 1 Association of baseline NTRI resistance mutations and viral failure after 12 weeks on HAART

Baseline resistance mutation codons

RNA > 400 at week 12

(N = 19)

RNA ≤ 400 at week 12

(N = 26)

RNA > 400 at week 12

(N = 22)

RNA ≤ 400 at week 12

(N = 25)

Total number (%) with a resistance mutation at baseline

(N = 92 children)

215

14

19

9^b

19^b

61 (66)

41

8

11

6

14

39 (42)

67

4

13

6

11

34 (37)

210

4

12

4

10

30 (33)

70

4

10

6

9

29 (32)

69

4

4

5

7

20 (22)

118

2

7

5

5

19 (21)

219

3

8

3

5

19 (21)

74

2

6

1

4

13 (14)

184

2

1

1

1

5 (5)

44

0

2

0

2

4 (4)

151

0

0

0

2

2 (2)

65

0

1

0

0

1 (1)

75

0

1

0

0

1 (1)

116

0

0

0

1

1 (1)

Any NRTI

16

23

15

23

77 (84)

Any PI or NRTI

19

25

21

25

90 (98)