Table 2 Relative hazard of HAART discontinuation (including downshifting) and HAART switching among participants initiating HAART prior to 10/1/04

§Model 1:

§Model 2:

§Model 2 Restricting to data contributed after Jan 1999

§Model 1:

§Model 2:

Univariate

Multivariate

Multivariate

Univariate

Multivariate

1.78 (1.53–2.06)

1.24 (1.03–1.48)

1.05 (0.81–1.36)

0.96 (0.82–1.14)

1.09 (0.89–1.34)

0.94 (0.85–1.03)

1.03 (0.93–1.15)

0.98 (0.84–1.15)

0.94 (0.84–1.04)

1.02 (0.91–1.14)

2.41 (2.02–2.88)

1.84 (1.47–2.29)

1.87 (1.37–2.54)

0.99 (0.84–1.17)

1.19 (0.96–1.48)

2.33 (1.95–2.92)

1.96 (1.50–2.57)

1.74 (1.15–2.65)

1.35 (1.09–1.68)

1.44 (1.10–1.87)

2.86 (1.69–4.85)

2.39 (1.36–4.20)

2.64 (1.12–6.23)

1.18 (0.61–2.30)

1.20 (0.58–2.46)

0.51 (0.43–0.60)

0.85 (0.69–1.05)

1.01 (0.76–1.34)

1.00 (0.86–1.16)

1.17 (0.94–1.45)

1.23 (1.17–1.30)

1.39 (1.31–1.48)

1.48 (1.36–1.60)

1.18 (1.12–1.24)

1.28 (1.21–1.36)

1.28 (1.16–1.40)

1.34 (1.21–1.48)

1.34 (1.17–1.54)

1.27 (1.15–1.39)

1.32 (1.19–1.47)

1.26 (1.09–1.47)

0.96 (0.81–1.14)

0.88 (0.70–1.12)

1.17 (0.99–1.36)

1.08 (0.90–1.29)

0.77 (0.64–0.93)

0.85 (0.70–1.05)

0.70 (0.53–0.92)

0.63 (0.51–0.77)

0.66 (0.53–0.83)

1.07 (0.90–1.26)

1.07 (0.89–1.28)

1.13 (0.89–1.44)

0.79 (0.66–0.95)

0.81 (0.66–0.99)

1.85 (1.59–2.15)

1.47 (1.20–1.71)

1.39 (1.05–1.84)

0.96 (0.82–1.12)

1.09 (0.91–1.30)

0.49 (0.42–0.58)

0.81 (0.67–0.98)

0.84 (0.64–1.09)

0.80 (0.68–0.93)

0.87 (0.72–1.05)

2.33 (2.00–2.72)

1.44 (1.20–1.78)

1.39 (1.05–1.84)

1.21 (1.04–1.41)

1.18 (0.97–1.44)