TLC Lower threshold | TLC Upper threshold | Hb threshold | BMI threshold | Sensitivity for CD4 <350 | Specificity for CD4 <350 | accuracy | sensitivity for CD4<200 | False Positives | N Qualifying For ART |
---|---|---|---|---|---|---|---|---|---|
A) CD4 alone | 1.00 | 1.00 | 1.00 | 1.00 | 0 | 1230 | |||
B) TLC alone | |||||||||
1500 | 0.40 | 0.95 | 0.67 | 519 | |||||
1750 | 0.59 | 0.85 | 0.67 | 0.69 | 0.11 | 801 | |||
2000 | 0.71 | 0.69 | 0.71 | 0.80 | 0.17 | 1043 | |||
*2250 | 0.81 | 0.54 | 0.73 | 0.88 | 0.21 | 1250 | |||
2500 | 0.88 | 0.41 | 0.73 | 0.93 | 0.24 | 1404 | |||
2750 | 0.92 | 0.28 | 0.72 | 0.96 | 0.27 | 1523 | |||
3000 | 0.95 | 0.21 | 0.71 | 0.97 | 0.28 | 1601 | |||
C) TLC combined with Hb and/or BMI | |||||||||
1750 | 2750 | 11 | 0.71 | 0.75 | 0.68 | 0.81 | 0.14 | 1017 | |
1750 | 2750 | 12 | 0.78 | 0.62 | 0.73 | 0.86 | 0.18 | 1180 | |
1750 | 2750 | 18 | 0.64 | 0.77 | 0.68 | 0.75 | 0.14 | 917 | |
1750 | 2750 | 11 | 18 | 0.74 | 0.69 | 0.73 | 0.84 | 0.16 | 1087 |
*2000 | 3000 | 11 | 0.81 | 0.62 | 0.75 | 0.88 | 0.18 | 1212 | |
2000 | 3000 | 12 | 0.85 | 0.51 | 0.74 | 0.94 | 0.21 | 1335 | |
2000 | 3000 | 18 | 0.75 | 0.63 | 0.72 | 0.84 | 0.19 | 1138 | |
**2000 | 3000 | 11 | 18 | 0.83 | 0.57 | 0.75 | 0.90 | 0.20 | 1268 |
1750 | 2500 | 11 | 0.69 | 0.76 | 0.72 | 0.79 | 0.14 | 989 | |
1750 | 2500 | 12 | 0.79 | 0.61 | 0.73 | 0.84 | 0.20 | 1169 | |
1750 | 2500 | 11 | 18 | 0.72 | 0.72 | 0.72 | 0.82 | 0.15 | 1045 |
2000 | 2750 | 11 | 0.79 | 0.62 | 0.74 | 0.86 | 0.18 | 1190 | |
2000 | 2750 | 18 | 0.75 | 0.64 | 0.71 | 0.83 | 0.19 | 1128 | |
2000 | 2750 | 11 | 18 | 0.81 | 0.57 | 0.74 | 0.89 | 0.20 | 1242 |
D) TLC combined with Hb and/or BMI for WHO stages I and II only | |||||||||
**2000 | 3000 | 11 | 0.80 | 0.62 | 0.74 | 0.93 | 0.19 | 1282‡ | |
2000 | 3000 | 11 | 18 | 0.83 | 0.57 | 0.73 | 0.90 | 0.20 | 1328‡ |
E) TLC combined with Hb and/or BMI for men only | |||||||||
2000 | 3000 | 11 | 0.58 | 0.71 | 0.72 | 0.80 | 0.12 | ||
2000 | 3000 | 12 | 0.76 | 0.63 | 0.73 | 0.84 | 0.14 | ||
2000 | 3000 | 11 | 18 | 0.77 | 0.60 | 0.73 | 0.87 | 0.14 | |
**2000 | 3000 | 12 | 18 | 0.80 | 0.57 | 0.75 | 0.89 | 0.15 |