Assessing the effect of HAART on change in quality of life among HIV-infected women

Liu, Chenglong; Weber, Kathleen; Robison, Esther; Hu, Zheng; Jacobson, Lisa P; Gange, Stephen J

doi:10.1186/1742-6405-3-6

AIDS Research and Therapy

Table 2 Estimates of the Impact of HAART on the Mean Change in QOL Scores from Propensity-Score Matched Pattern Mixture Models.

From: Assessing the effect of HAART on change in quality of life among HIV-infected women

		Model 1^a		Model 2^b		Model 3^c		Model 4^d		Model 5^e
		Effect	P-Value	Effect	P-Value	Effect	P-Value	Effect	P-Value	Effect	P-Value
Summary QOL Score	Short-Term HAART Effect	2.07	0.11	2.25	0.07	2.26	0.07	2.24	0.08	3.25	0.02
	Change per 6 months	-0.30	0.01	-0.30	0.01	-0.21	0.08	-0.29	0.02	-0.29	0.01
Physical functioning	Short-Term HAART Effect	0.71	0.70	0.72	0.70	0.83	0.66	0.15	0.94	1.86	0.35
	Change per 6 months	-0.39	0.02	-0.39	0.02	-0.28	0.14	-0.36	0.07	-0.30	0.10
Role functioning	Short-Term HAART Effect	5.08	0.01	5.40	0.01	5.46	0.01	5.98	0.01	6.99	0.00
	Change per 6 months	-0.40	0.04	-0.36	0.07	-0.34	0.11	-0.47	0.03	-0.45	0.04
Energy/fatigue	Short-Term HAART Effect	-0.09	0.96	0.37	0.83	0.32	0.86	0.43	0.81	1.24	0.51
	Change per 6 months	-0.30	0.06	-0.31	0.05	-0.19	0.28	-0.21	0.24	-0.26	0.13
Social functioning	Short-Term HAART Effect	4.33	0.01	4.96	0.00	4.90	0.01	5.03	0.01	5.74	0.00
	Change per 6 months	-0.22	0.19	-0.19	0.25	-0.13	0.47	-0.19	0.30	-0.19	0.30
Cognitive functioning	Short-Term HAART Effect	2.58	0.08	3.51	0.02	3.46	0.02	3.48	0.03	3.59	0.03
	Change per 6 months	-0.08	0.57	-0.07	0.61	0.07	0.64	0.04	0.78	-0.04	0.82
Pain	Short-Term HAART Effect	4.53	0.01	4.33	0.02	4.33	0.02	4.65	0.02	6.73	0.00
	Change per 6 months	-0.25	0.15	-0.26	0.14	-0.10	0.58	-0.21	0.29	-0.19	0.32
Emotional well-being	Short-Term HAART Effect	2.38	0.12	2.46	0.12	2.47	0.12	2.45	0.12	2.05	0.20
	Change per 6 months	-0.16	0.25	-0.17	0.23	-0.18	0.23	-0.26	0.11	-0.30	0.05
Health perception	Short-Term HAART Effect	2.60	0.10	3.05	0.06	3.04	0.06	3.43	0.04	3.67	0.03
	Change per 6 months	-0.49	0.00	-0.49	0.00	-0.45	0.00	-0.50	0.00	-0.53	0.00
Perceived health index	Short-Term HAART Effect	4.25	0.00	4.79	0.00	4.67	0.00	4.65	0.00	4.87	0.00
	Change per 6 months	-0.08	0.86	-0.09	0.87	-0.11	0.87	-0.11	0.84	-0.09	0.83

^aModel 1: Model includes an intercept, an indicator of HAART or HAART-naïve group (Short-Term HAART Effect) and the time from index visit (Change per 6 months).
^bModel 2: Model 1 + age, ethnicity and education level.
^cModel 3: Model 2 + income, employment and health insurance.
^dModel 4: Model 3+ CD4+ cell counts and viral load.
^eModel 5: Model 4+ number of symptoms, outpatient visits, hospitalizations and medication, AIDS history and clinical depression. Interactions between HAART and time from index visit were not statistically significant for all models.

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ISSN: 1742-6405

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