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Table 1 Demographic Data and Results

From: Use of taste-masking product, FLAVORx, to assist Thai children to ingest generic antiretrovirals

No. gender Age (y) Wt (Kg) Ht (cm) CDC CD4% (cell/mm3) Regimen* Chosen flavors NNRTI Trough level **(mg/L) Reason of discontinue FLAVORx
         VisitI VisitII VisitI VisitII  
1 F 6.7 16 112.5 B 13%(277) AZT 1cap+7 mlX2 3TC 1/2 tabX2 NVP 3/4 tabX2 S x 3.94 4.19 Spicy taste
2 M 5.5 17 111 B 39%(1108) AZT 1 cap +6 mlX2 3TC 7 mlX2 NVP 3/4 tabX2 S, O x 14.80 7.01 Child prefer to mix ARV with water
3 F 3.5 12.5 92.5 A 7%(342) 3TC 5 mlX2 EFV 200 mg d4T 1/3 tabx2 O x 11.88 8.29 Spicy taste
4 F 4.2 14 97 A 10%(210) AZT 1 cap +5 mlx2 3TC 6 mlx2 EFV 200 mg S S 2.14 1.55  
5 M 4.8 17.2 106 A 24%(1122) AZT 1 cap +7 mlX2 3TC 1 tab X2 NVP 3/4 tabX2 S, O S,G 5.66 5.60  
6 M 5.3 12.5 93 B 6%(459) AZT 1 cap +4 mlX2 3TC 5 mlx2 NVP 1/2 tabx2 S S 3.05 3.45  
7 F 4.5 14 99 C 17%(356) AZT 1 cap +5 mlX2 ddI(170 mg) 1 × 1 S,O,G G - -  
8 M 4 15 96 A 42%(2278) AZT 1 cap +5 ml 3TC 6 mlx2 EFV 200 mg S x 1.93 2.45 Vomiting
9 F 7.5 29.6 126 A 29%(614) AZT 2 cap X2 3TC 1 tab X2 EFV 350 mg S x - - Child prefer to mix ARV with water
10 M 4.1 15 99 C 22%(945) AZT 1 cap +5 mlX2 3TC 7 mlX2 EFV 250 mg S,O S 3.18 0.00 Repeat ***  
11 F 4.6 23 106 A 25%(1224) 3TC 1 tab x2 EFV 300 mg ddI(115) 2 × 1 S S 1.40 3.78  
12 M 1 11.5 84.5 C 38%(1732) 3TC 4 mlx2 NVP 1/2 tab X2 d4T 10 mgx2 O S,G,B 3.51 4.30  
13 F 4.8 14.1 97 A 35%(1428) AZT 1 cap +5 mlX2 3TC 1 tabX2 EFV 250 mg S S,B    
14 F 2 10.2 83 B 24%(761) AZT 1 cap +2 ml × 2 3TC 5 ml × 2 Kaletra 1.4 ml × 2 O S    
15 F 4.7 11.6 93 B 15%(250) 3TC 6 mlX2 NVP 1/2 tabX2 d4T 15 mgx2 S S    
16 M 4 13.9 95.5 C 24%(960) AZT 1 cap +4 mlx2 3TC 6 mlx2 EFV 200 mg S S    
17 F 5.5 14 104 B 22%(591) AZT 1 cap +4 mlX2 3TC 1/2 tab x2 NVP 3/4 tabx2 S S    
18 M 4.3 15.1 103 C 26%(1261) AZT 1 cap +5 mlX2 3TC 7 mlX2 EFV 200 mg S S    
19 M 7.7 17.5 105 B 23%(915) 3TC 1/2 tabX2 EFV 250 mg d4T 15 mgX2 O,G G    
20 F 5.4 20 105.5 B 41%(1137) AZT 1 cap +5 mlX2 3TC 1tabX2 EFV 250 mg S,O B,A    
21 F 9.8 18 119 B 27%(1086) AZT 1 cap +8 mlX2 3TC 1 tabX2 EFV 300 mg O,G G    
22 F 8.8 18 116.5 B 6%(112) AZT 1 cap +8 mlX2 3TC 1/2 tabX2 NVP 3/4 tabX2 S G    
23 F 1.8 10 82 A 33%(1933) AZT 1 cap +1 mlx2 3TC 5 mlX2 Kaletra 1.4 ml × 2 S,O O    
24 M 8 22.6 119 B 25%(809) 3TC 1 tabX2 d4T 1/2 tabx2 NVP 3/4 tab x2 S,O x    Child prefer to mix ARV with water
25 F 4 15.2 94 B 28%(817) 3TC 1/2 tabX2 EFV 200 mg d4T 15 mg S,B S,B    
26 F 6.3 16.9 109 C 26%(723) AZT 1 cap +5 mlX2 3TC 1/2 tabX2 NVP 3/4 tabX2 O O    
27 F 6.7 18.3 110 C 40%(1109) 3TC 7 mlX2 EFV 250 mg d4T 15 mg S,O B    
28 M 4.5 15 102.5 A 28%(1076) 3TC 1/2 tabX2 EFV 200 mg d4T 15 mgX2 G G    
29 F 6 19.2 110 A 12%(551) AZT 1 cap +8 mlX2 3TC 1/2 tab X2 NVP 3/4 tabX2 S,O G    
30 M 5.7 20 114 C 17%(345) AZT 1 cap +8 mlX2 3TC 1 tabX2 EFV 300 mg S S    
  1. * The bolded drugs were mixed with FLAVORx
  2. ** compare to NNRTI target serum level: for NVP is 3.4 mg/l, EFV is 1.0 mg/l (Ref: John G. Bartlett, John Hopkins University School of Medicine, Pocket Guide to adult HIV/AIDS treatment, Jan 2005.
  3. *** Repeat trough level without using FLAVORx = 3.74 mg/l
  4. Chosen Taste: S = strawberry, O = orange, G = grape, B = banana, A = apple, X = children or parent did not want to continue FLAVORx
  5. Cap = capsule, tab = tablet