Figure 4
From: Post-exposure prophylaxis for SIV revisited: Animal model for HIV prevention
Relationship between levels of CD8+ cells in peripheral blood and plasma viral load in macaques during in vivo depletion of CD8+ lymphocytes. Depletion of CD8+ lymphocytes was achieved by using the monoclonal anti-CD8 antibody (cMT807) as described in the text. Depletion studies were performed 2.3 years after the end of PMPA-treatment. Levels of CD8+ lymphocytes were measured by flow cytometry and plasma viral load was quantitated by a branched DNA (bDNA) signal amplification assay for SIV as described in the text. Macaque 93217 and 93194 were from group C. Macaque 93040 and 93043 were from group D.