Figure 3
From: Post-exposure prophylaxis for SIV revisited: Animal model for HIV prevention
Anti-SIV IgG antibody response in untreated and PMPA-treated macaques after intravenous inoculation with uncloned SIVmne. Group A were naïve untreated macaques. Macaques in group B (plus macaque 93043 in group D) received a 10-week PMPA treatment beginning 24 hours after virus inoculation, including treatment interruption plus SIVmne re-inoculation at weekly intervals during the first six weeks of treatment. Macaques in groups C and D received a 5-week PMPA treatment starting 24 hours after virus inoculation, including one treatment interruption plus SIVmne re-inoculation at week 1 of treatment. Titers are expressed as the reciprocal of the highest dilution that was positive by HIV-2 EIA (Sanofi-Pasteur, Redmond, WA). The lowest plasma dilution used was 1:40.