Table 1 Variations in HLA-G DNA sequence observed among HIV-1-transmitting and non-transmitting mother-child pairs.

5'URR

---

634 C/G

C→G

None

5'URR

---

714 ins T,G

insT,G

None

2 α-1-domain

31

1074 A/T

A→T

Thr-to-Ser

2 α-1-domain

57

1154 G/A

G→A

Pro-to-Pro

3 α-2-domain

93

1486 C/G

C→G

His-to-Asp

3 α-2-domain

93

1486 C/A

C→A

His-to-Asp

3 α-2-domain

93

1488 C/T

C→T

None (His)

3 α-2-domain

107

1528 G/A

G→A

Gly-to-Arg

3 α-2-domain

110

1537 C/A

C→A

Leu-to-Ile

3 α-2-domain

130

1597 del C

del C

Leu→frameshift

4 α-3-domain

256

2575 G/A

G→A

Arg-to-Lys

4 α-3-domain

257

2577 T/A

T→A

Tyr-to-Asn

4 α-3-domain

269

2614 C/A

C→A

Pro-to-His

4 α-3-domain

272

2622 C/A

C→A

Leu-to-Met

Intron 6

3401 ins C

ins C

None

Intron 7

3579 G/A

G→A

None

3585 G/T

G→T

None

3619 C/G

C→G

None

8 (3'UTR)

3742 T/A

T→A

instability of mRNA

8 (3'UTR)

3743 C/T

Del 14 bp

instability of mRNA

8 (3'UTR)

3777 G/C

G→C

instability of mRNA